Thomas Pertel
Thomas Pertel
Allogene Therapeutics
Verified email at - Homepage
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IFITM3 restricts the morbidity and mortality associated with influenza
AR Everitt, S Clare, T Pertel, SP John, RS Wash, SE Smith, CR Chin, ...
Nature 484 (7395), 519-523, 2012
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
T Pertel, S Hausmann, D Morger, S Züger, J Guerra, J Lascano, ...
Nature 472 (7343), 361-365, 2011
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
YH Huang, C Zhu, Y Kondo, AC Anderson, A Gandhi, A Russell, ...
Nature 517 (7534), 386-390, 2015
IFITM3 inhibits influenza A virus infection by preventing cytosolic entry
EM Feeley, JS Sims, SP John, CR Chin, T Pertel, LM Chen, GD Gaiha, ...
PLoS pathogens 7 (10), e1002337, 2011
Impairment of NK cell function by NKG2D modulation in NOD mice
K Ogasawara, JA Hamerman, H Hsin, S Chikuma, H Bour-Jordan, T Chen, ...
Immunity 18 (1), 41-51, 2003
HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome
DZ Soghoian, H Jessen, M Flanders, K Sierra-Davidson, S Cutler, T Pertel, ...
Science translational medicine 4 (123), 123ra25-123ra25, 2012
Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics
A Kaul, S Stauffer, C Berger, T Pertel, J Schmitt, S Kallis, M Zayas Lopez, ...
PLoS pathogens 5 (8), e1000546, 2009
Reactivation of latent HIV-1 by inhibition of BRD4
J Zhu, GD Gaiha, SP John, T Pertel, CR Chin, G Gao, H Qu, BD Walker, ...
Cell reports 2 (4), 807-816, 2012
An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction
C Zhu, K Sakuishi, S Xiao, Z Sun, S Zaghouani, G Gu, C Wang, DJ Tan, ...
Nature communications 6 (1), 6072, 2015
Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1
WF Garcia-Beltran, A Hölzemer, G Martrus, AW Chung, Y Pacheco, ...
Nature immunology 17 (9), 1067-1074, 2016
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity
PD Uchil, A Hinz, S Siegel, A Coenen-Stass, T Pertel, J Luban, W Mothes
Journal of virology 87 (1), 257-272, 2013
The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication
SP John, CR Chin, JM Perreira, EM Feeley, AM Aker, G Savidis, SE Smith, ...
Journal of virology 87 (14), 7837-7852, 2013
Characterization of Simian Immunodeficiency Virus SIVSM/Human Immunodeficiency Virus Type 2 Vpx Function in Human Myeloid Cells
C Goujon, V Arfi, T Pertel, J Luban, J Lienard, D Rigal, JL Darlix, ...
Journal of virology 82 (24), 12335-12345, 2008
Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components
MR Neagu, P Ziegler, T Pertel, C Strambio-De-Castillia, C Grütter, ...
The Journal of clinical investigation 119 (10), 3035-3047, 2009
A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal
R Bernasconi, T Pertel, J Luban, M Molinari
Journal of Biological Chemistry 283 (24), 16446-16454, 2008
Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells
LS Einbond, M Shimizu, D Xiao, P Nuntanakorn, JTE Lim, M Suzui, ...
Breast cancer research and treatment 83, 221-231, 2004
TRIM22 inhibits HIV-1 transcription independently of its E3 ubiquitin ligase activity, Tat, and NF-κB-responsive long terminal repeat elements
A Kajaste-Rudnitski, SS Marelli, C Pultrone, T Pertel, PD Uchil, N Mechti, ...
Journal of virology 85 (10), 5183-5196, 2011
Preclinical evaluation of allogeneic CAR T cells targeting BCMA for the treatment of multiple myeloma
C Sommer, B Boldajipour, TC Kuo, T Bentley, J Sutton, A Chen, T Geng, ...
Molecular therapy 27 (6), 1126-1138, 2019
Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy
CA Sabatos-Peyton, J Nevin, A Brock, JD Venable, DJ Tan, N Kassam, ...
Oncoimmunology 7 (2), e1385690, 2018
Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1
E Van Anken, F Pena, N Hafkemeijer, C Christis, EP Romijn, ...
Proceedings of the National Academy of Sciences 106 (40), 17019-17024, 2009
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