| Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report JF Arboleda-Velasquez, F Lopera, M O’Hare, S Delgado-Tirado, C Marino, ... Nature medicine 25 (11), 1680-1683, 2019 | 468 | 2019 |
| Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study EM Reiman, JF Arboleda-Velasquez, YT Quiroz, MJ Huentelman, ... Nature communications 11 (1), 667, 2020 | 330 | 2020 |
| Delta-like 4 induces notch signaling in macrophages: implications for inflammation E Fung, SMT Tang, JP Canner, K Morishige, JF Arboleda-Velasquez, ... Circulation 115 (23), 2948-2956, 2007 | 272 | 2007 |
| Association between amyloid and tau accumulation in young adults with autosomal dominant Alzheimer disease YT Quiroz, RA Sperling, DJ Norton, A Baena, JF Arboleda-Velasquez, ... JAMA neurology 75 (5), 548-556, 2018 | 171 | 2018 |
| Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease JF Arboleda-Velasquez, J Manent, JH Lee, S Tikka, C Ospina, ... Proceedings of the National Academy of Sciences 108 (21), E128-E135, 2011 | 140 | 2011 |
| Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study YT Quiroz, H Zetterberg, EM Reiman, Y Chen, Y Su, JT Fox-Fuller, ... The Lancet Neurology 19 (6), 513-521, 2020 | 133 | 2020 |
| Brain imaging and blood biomarker abnormalities in children with autosomal dominant Alzheimer disease: a cross-sectional study YT Quiroz, AP Schultz, K Chen, HD Protas, M Brickhouse, AS Fleisher, ... JAMA neurology 72 (8), 912-919, 2015 | 127 | 2015 |
| Highly Conserved O-Fucose Sites Have Distinct Effects on Notch1 Function*♦ R Rampal, JF Arboleda-Velasquez, A Nita-Lazar, KS Kosik, ... Journal of Biological Chemistry 280 (37), 32133-32140, 2005 | 127 | 2005 |
| Linking Notch signaling to ischemic stroke JF Arboleda-Velasquez, Z Zhou, HK Shin, A Louvi, HH Kim, SI Savitz, ... Proceedings of the National Academy of Sciences 105 (12), 4856-4861, 2008 | 121 | 2008 |
| C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke JF Arboleda–Velasquez, F Lopera, E Lopez, MP Frosch, ... Neurology 59 (2), 277-279, 2002 | 101 | 2002 |
| CADASIL: a critical look at a Notch disease A Louvi, JF Arboleda-Velasquez, S Artavanis-Tsakonas Developmental neuroscience 28 (1-2), 5-12, 2006 | 96 | 2006 |
| Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man F Lopera, C Marino, AS Chandrahas, M O’Hare, ND Villalba-Moreno, ... Nature medicine 29 (5), 1243-1252, 2023 | 79 | 2023 |
| CADASIL mutations impair Notch3 glycosylation by Fringe JF Arboleda-Velasquez, R Rampal, E Fung, DC Darland, M Liu, ... Human molecular genetics 14 (12), 1631-1639, 2005 | 70 | 2005 |
| Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL AI Machuca-Parra, AA Bigger-Allen, AV Sanchez, A Boutabla, ... Journal of Experimental Medicine 214 (8), 2271-2282, 2017 | 69 | 2017 |
| Identification of RUNX1 as a mediator of aberrant retinal angiogenesis JD Lam, DJ Oh, LL Wong, D Amarnani, C Park-Windhol, AV Sanchez, ... Diabetes 66 (7), 1950-1956, 2017 | 67 | 2017 |
| From pathobiology to the targeting of pericytes for the treatment of diabetic retinopathy JF Arboleda-Velasquez, CN Valdez, CK Marko, PA D’Amore Current diabetes reports 15, 1-10, 2015 | 63 | 2015 |
| Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia D Sepulveda-Falla, JS Sanchez, MC Almeida, D Boassa, J Acosta-Uribe, ... Acta neuropathologica 144 (3), 589-601, 2022 | 54 | 2022 |
| Effect of methotrexate on an in vitro patient-derived model of proliferative vitreoretinopathy D Amarnani, AI Machuca-Parra, LL Wong, CK Marko, JA Stefater, ... Investigative Ophthalmology & Visual Science 58 (10), 3940-3949, 2017 | 51 | 2017 |
| TNF‐α signaling regulates RUNX1 function in endothelial cells HAB Whitmore, D Amarnani, M O'Hare, S Delgado‐Tirado, ... The FASEB Journal 35 (2), 2021 | 44 | 2021 |
| Whole exome sequencing identification of novel candidate genes in patients with proliferative diabetic retinopathy C Ung, AV Sanchez, L Shen, S Davoudi, T Ahmadi, D Navarro-Gomez, ... Vision research 139, 168-176, 2017 | 43 | 2017 |
Francisco LoperaFull Professor of University of AntioquiaVerified email at gna.org.co
