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Michelle W. Lee
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Helical antimicrobial polypeptides with radial amphiphilicity
M Xiong, MW Lee, RA Mansbach, Z Song, Y Bao, RM Peek Jr, C Yao, ...
Proceedings of the National Academy of Sciences 112 (43), 13155-13160, 2015
2012015
What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning?
EY Lee, MW Lee, BM Fulan, AL Ferguson, GCL Wong
Interface focus 7 (6), 20160153, 2017
1302017
Modulation of toll-like receptor signaling by antimicrobial peptides
EY Lee, MW Lee, GCL Wong
Seminars in cell & developmental biology 88, 173-184, 2019
872019
Direct antimicrobial activity of IFN-β
A Kaplan, MW Lee, AJ Wolf, JJ Limon, CA Becker, M Ding, R Murali, ...
The Journal of Immunology 198 (10), 4036-4045, 2017
742017
Viral fusion protein transmembrane domain adopts β-strand structure to facilitate membrane topological changes for virus–cell fusion
H Yao, MW Lee, AJ Waring, GCL Wong, M Hong
Proceedings of the National Academy of Sciences 112 (35), 10926-10931, 2015
722015
Interactions between membranes and “metaphilic” polypeptide architectures with diverse side-chain populations
MW Lee, M Han, GV Bossa, C Snell, Z Song, H Tang, L Yin, J Cheng, ...
ACS nano 11 (3), 2858-2871, 2017
492017
Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes
Y Zhang, V Bharathi, T Dokoshi, J de Anda, LT Ursery, NN Kulkarni, ...
Proceedings of the National Academy of Sciences 121 (6), e2300644120, 2024
432024
Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides
MW Lee, S Chakraborty, NW Schmidt, R Murgai, SH Gellman, GCL Wong
Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (9), 2269-2279, 2014
432014
Unifying structural signature of eukaryotic α-helical host defense peptides
NY Yount, DC Weaver, EY Lee, MW Lee, H Wang, LC Chan, GCL Wong, ...
Proceedings of the National Academy of Sciences 116 (14), 6944-6953, 2019
422019
Molecular motor Dnm1 synergistically induces membrane curvature to facilitate mitochondrial fission
MW Lee, EY Lee, GH Lai, NW Kennedy, AE Posey, W Xian, AL Ferguson, ...
ACS central science 3 (11), 1156-1167, 2017
352017
Machine learning antimicrobial peptide sequences: Some surprising variations on the theme of amphiphilic assembly
MW Lee, EY Lee, AL Ferguson, GCL Wong
Current opinion in colloid & interface science 38, 204-213, 2018
262018
Discovery of novel type II bacteriocins using a new high-dimensional bioinformatic algorithm
NY Yount, DC Weaver, J De Anda, EY Lee, MW Lee, GCL Wong, ...
Frontiers in Immunology 11, 1873, 2020
212020
Highly basic clusters in the herpes simplex virus 1 nuclear egress complex drive membrane budding by inducing lipid ordering
MK Thorsen, A Lai, MW Lee, DP Hoogerheide, GCL Wong, JH Freed, ...
MBio 12 (4), 10.1128/mbio. 01548-21, 2021
172021
Chemokine CCL28 is a potent therapeutic agent for oropharyngeal candidiasis
J He, MA Thomas, J De Anda, MW Lee, E Van Why, P Simpson, ...
Antimicrobial agents and chemotherapy 64 (8), 10.1128/aac. 00210-20, 2020
122020
How do cyclic antibiotics with activity against Gram-negative bacteria permeate membranes? A machine learning informed experimental study
MW Lee, J de Anda, C Kroll, C Bieniossek, K Bradley, KE Amrein, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (8), 183302, 2020
112020
Histidine‐Mediated Ion Specific Effects Enable Salt Tolerance of a Pore‐Forming Marine Antimicrobial Peptide
W Xian, MR Hennefarth, MW Lee, T Do, EY Lee, AN Alexandrova, ...
Angewandte Chemie International Edition 61 (25), e202108501, 2022
102022
Switchable membrane remodeling and antifungal defense by metamorphic chemokine XCL1
AF Dishman, MW Lee, J de Anda, EY Lee, J He, AR Huppler, GCL Wong, ...
ACS Infectious Diseases 6 (5), 1204-1213, 2020
102020
What can pleiotropic proteins in innate immunity teach us about bioconjugation and molecular design?
MW Lee, EY Lee, GCL Wong
Bioconjugate chemistry 29 (7), 2127-2139, 2018
92018
Apolipoprotein mimetic peptide inhibits neutrophil-driven inflammatory damage via membrane remodeling and suppression of cell lysis
MW Lee, EWC Luo, C Silvestre-Roig, Y Srinivasan, K Akabori, ...
ACS nano 15 (10), 15930-15939, 2021
82021
Mechanisms of membrane curvature generation by peptides and proteins: A unified perspective on antimicrobial peptides
MW Lee, NW Schmidt, GCL Wong
Handbook of Lipid Membranes, 141-159, 2021
42021
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Articles 1–20