Helical antimicrobial polypeptides with radial amphiphilicity M Xiong, MW Lee, RA Mansbach, Z Song, Y Bao, RM Peek Jr, C Yao, ... Proceedings of the National Academy of Sciences 112 (43), 13155-13160, 2015 | 201 | 2015 |
What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning? EY Lee, MW Lee, BM Fulan, AL Ferguson, GCL Wong Interface focus 7 (6), 20160153, 2017 | 130 | 2017 |
Modulation of toll-like receptor signaling by antimicrobial peptides EY Lee, MW Lee, GCL Wong Seminars in cell & developmental biology 88, 173-184, 2019 | 87 | 2019 |
Direct antimicrobial activity of IFN-β A Kaplan, MW Lee, AJ Wolf, JJ Limon, CA Becker, M Ding, R Murali, ... The Journal of Immunology 198 (10), 4036-4045, 2017 | 74 | 2017 |
Viral fusion protein transmembrane domain adopts β-strand structure to facilitate membrane topological changes for virus–cell fusion H Yao, MW Lee, AJ Waring, GCL Wong, M Hong Proceedings of the National Academy of Sciences 112 (35), 10926-10931, 2015 | 72 | 2015 |
Interactions between membranes and “metaphilic” polypeptide architectures with diverse side-chain populations MW Lee, M Han, GV Bossa, C Snell, Z Song, H Tang, L Yin, J Cheng, ... ACS nano 11 (3), 2858-2871, 2017 | 49 | 2017 |
Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Y Zhang, V Bharathi, T Dokoshi, J de Anda, LT Ursery, NN Kulkarni, ... Proceedings of the National Academy of Sciences 121 (6), e2300644120, 2024 | 43 | 2024 |
Two interdependent mechanisms of antimicrobial activity allow for efficient killing in nylon-3-based polymeric mimics of innate immunity peptides MW Lee, S Chakraborty, NW Schmidt, R Murgai, SH Gellman, GCL Wong Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (9), 2269-2279, 2014 | 43 | 2014 |
Unifying structural signature of eukaryotic α-helical host defense peptides NY Yount, DC Weaver, EY Lee, MW Lee, H Wang, LC Chan, GCL Wong, ... Proceedings of the National Academy of Sciences 116 (14), 6944-6953, 2019 | 42 | 2019 |
Molecular motor Dnm1 synergistically induces membrane curvature to facilitate mitochondrial fission MW Lee, EY Lee, GH Lai, NW Kennedy, AE Posey, W Xian, AL Ferguson, ... ACS central science 3 (11), 1156-1167, 2017 | 35 | 2017 |
Machine learning antimicrobial peptide sequences: Some surprising variations on the theme of amphiphilic assembly MW Lee, EY Lee, AL Ferguson, GCL Wong Current opinion in colloid & interface science 38, 204-213, 2018 | 26 | 2018 |
Discovery of novel type II bacteriocins using a new high-dimensional bioinformatic algorithm NY Yount, DC Weaver, J De Anda, EY Lee, MW Lee, GCL Wong, ... Frontiers in Immunology 11, 1873, 2020 | 21 | 2020 |
Highly basic clusters in the herpes simplex virus 1 nuclear egress complex drive membrane budding by inducing lipid ordering MK Thorsen, A Lai, MW Lee, DP Hoogerheide, GCL Wong, JH Freed, ... MBio 12 (4), 10.1128/mbio. 01548-21, 2021 | 17 | 2021 |
Chemokine CCL28 is a potent therapeutic agent for oropharyngeal candidiasis J He, MA Thomas, J De Anda, MW Lee, E Van Why, P Simpson, ... Antimicrobial agents and chemotherapy 64 (8), 10.1128/aac. 00210-20, 2020 | 12 | 2020 |
How do cyclic antibiotics with activity against Gram-negative bacteria permeate membranes? A machine learning informed experimental study MW Lee, J de Anda, C Kroll, C Bieniossek, K Bradley, KE Amrein, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (8), 183302, 2020 | 11 | 2020 |
Histidine‐Mediated Ion Specific Effects Enable Salt Tolerance of a Pore‐Forming Marine Antimicrobial Peptide W Xian, MR Hennefarth, MW Lee, T Do, EY Lee, AN Alexandrova, ... Angewandte Chemie International Edition 61 (25), e202108501, 2022 | 10 | 2022 |
Switchable membrane remodeling and antifungal defense by metamorphic chemokine XCL1 AF Dishman, MW Lee, J de Anda, EY Lee, J He, AR Huppler, GCL Wong, ... ACS Infectious Diseases 6 (5), 1204-1213, 2020 | 10 | 2020 |
What can pleiotropic proteins in innate immunity teach us about bioconjugation and molecular design? MW Lee, EY Lee, GCL Wong Bioconjugate chemistry 29 (7), 2127-2139, 2018 | 9 | 2018 |
Apolipoprotein mimetic peptide inhibits neutrophil-driven inflammatory damage via membrane remodeling and suppression of cell lysis MW Lee, EWC Luo, C Silvestre-Roig, Y Srinivasan, K Akabori, ... ACS nano 15 (10), 15930-15939, 2021 | 8 | 2021 |
Mechanisms of membrane curvature generation by peptides and proteins: A unified perspective on antimicrobial peptides MW Lee, NW Schmidt, GCL Wong Handbook of Lipid Membranes, 141-159, 2021 | 4 | 2021 |