Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils J Gotz, F Chen, J Van Dorpe, RM Nitsch Science 293 (5534), 1491-1495, 2001 | 2046 | 2001 |
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration B Oosthuyse, L Moons, E Storkebaum, H Beck, D Nuyens, K Brusselmans, ... Nature genetics 28 (2), 131-138, 2001 | 1377 | 2001 |
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein K Spittaels, C Van den Haute, JO Van Dorpe, K Bruynseels, ... The American journal of pathology 155 (6), 2153-2165, 1999 | 468 | 1999 |
Glycogen synthase kinase-3β phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice K Spittaels, C Van den Haute, JO Van Dorpe, H Geerts, M Mercken, ... Journal of Biological Chemistry 275 (52), 41340-41349, 2000 | 414 | 2000 |
Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice I Tesseur, J Van Dorpe, K Spittaels, C Van den Haute, D Moechars, ... The American journal of pathology 156 (3), 951-964, 2000 | 317 | 2000 |
Reduction of amyloid load and cerebral damage in transgenic mouse model of Alzheimer's disease by treatment with a β‐sheet breaker peptide B Permanne, C Adessi, GP Saborio, S Fraga, MJ Frossard, J Van Dorpe, ... The FASEB Journal 16 (8), 860-862, 2002 | 306 | 2002 |
Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the London mutant of human APP in neurons J Van Dorpe, L Smeijers, I Dewachter, D Nuyens, K Spittaels, ... The American journal of pathology 157 (4), 1283-1298, 2000 | 270 | 2000 |
Placental tissue destruction and insufficiency from COVID-19 causes stillbirth and neonatal death from hypoxic-ischemic injury: a study of 68 cases with SARS-CoV-2 placentitis … DA Schwartz, E Avvad-Portari, P Babál, M Baldewijns, M Blomberg, ... Archives of pathology & laboratory medicine 146 (6), 660-676, 2022 | 204 | 2022 |
Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord I Tesseur, J Van Dorpe, K Bruynseels, F Bronfman, R Sciot, ... The American journal of pathology 157 (5), 1495-1510, 2000 | 182 | 2000 |
Neuropathology and Neurodegeneration in Rodent Brain Induced by Lentiviral Vectormediated Overexpression of α‐Synuclein E Lauwers, Z Debyser, J Van Dorpe, B De Strooper, B Nuttin, ... Brain pathology 13 (3), 364-372, 2003 | 163 | 2003 |
Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1 I Dewachter, J Van Dorpe, L Smeijers, M Gilis, C Kuiperi, I Laenen, ... Journal of Neuroscience 20 (17), 6452-6458, 2000 | 158 | 2000 |
Long-term outcomes and genetic predictors of response to metastasis-directed therapy versus observation in oligometastatic prostate cancer: analysis of STOMP and ORIOLE trials MP Deek, K Van der Eecken, P Sutera, RA Deek, V Fonteyne, AA Mendes, ... Journal of clinical oncology 40 (29), 3377-3382, 2022 | 157 | 2022 |
Is calcifying fibrous pseudotumor a late sclerosing stage of inflammatory myofibroblastic tumor? J Van Dorpe, N Ectors, K Geboes, A D'Hoore, R Sciot The American journal of surgical pathology 23 (3), 329-335, 1999 | 144 | 1999 |
Neonatal neuronal overexpression of glycogen synthase kinase-3β reduces brain size in transgenic mice K Spittaels, C Van den Haute, J Van Dorpe, D Terwel, K Vandezande, ... Neuroscience 113 (4), 797-808, 2002 | 137 | 2002 |
Shallow whole genome sequencing on circulating cell-free DNA allows reliable noninvasive copy-number profiling in neuroblastoma patients N Van Roy, M Van Der Linden, B Menten, A Dheedene, C Vandeputte, ... Clinical Cancer Research 23 (20), 6305-6314, 2017 | 129 | 2017 |
Angiopoietin‐2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease S Lefere, F Van de Velde, A Hoorens, S Raevens, S Van Campenhout, ... Hepatology 69 (3), 1087-1104, 2019 | 128 | 2019 |
WisecondorX: improved copy number detection for routine shallow whole-genome sequencing L Raman, A Dheedene, M De Smet, J Van Dorpe, B Menten Nucleic acids research 47 (4), 1605-1614, 2019 | 122 | 2019 |
Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice I Dewachter, J Van Dorpe, K Spittaels, I Tesseur, C Van Den Haute, ... Experimental gerontology 35 (6-7), 831-841, 2000 | 117 | 2000 |
Randomized phase 1 trial of pembrolizumab with sequential versus concomitant stereotactic body radiotherapy in metastatic urothelial carcinoma N Sundahl, G Vandekerkhove, K Decaestecker, A Meireson, ... European urology 75 (5), 707-711, 2019 | 113 | 2019 |
Impalpable invisible stage T1c prostate cancer: characteristics and clinical relevance in 100 radical prostatectomy specimens-a different view AAA Elgamal, HP Van Poppel, WM Van de Voorde, JA Van Dorpe, ... The Journal of urology 157 (1), 244-250, 1997 | 107 | 1997 |