Evolution of hormone-receptor complexity by molecular exploitation JT Bridgham, SM Carroll, JW Thornton Science 312 (5770), 97-101, 2006 | 688 | 2006 |
Galactose metabolic genes in yeast respond to a ratio of galactose and glucose R Escalante-Chong, Y Savir, SM Carroll, JB Ingraham, J Wang, CJ Marx, ... Proceedings of the National Academy of Sciences 112 (5), 1636-1641, 2015 | 135 | 2015 |
Evolution of hormone signaling in elasmobranchs by exploitation of promiscuous receptors SM Carroll, JT Bridgham, JW Thornton Molecular biology and evolution 25 (12), 2643-2652, 2008 | 102 | 2008 |
Mechanisms for the evolution of a derived function in the ancestral glucocorticoid receptor SM Carroll, EA Ortlund, JW Thornton PLoS genetics 7 (6), e1002117, 2011 | 85 | 2011 |
Evolution after introduction of a novel metabolic pathway consistently leads to restoration of wild-type physiology SM Carroll, CJ Marx PLoS genetics 9 (4), e1003427, 2013 | 64 | 2013 |
The E. coli molecular phenotype under different growth conditions MU Caglar, JR Houser, CS Barnhart, DR Boutz, SM Carroll, A Dasgupta, ... Scientific reports 7 (1), 45303, 2017 | 55 | 2017 |
A novel pair of inducible expression vectors for use in Methylobacterium extorquens LM Chubiz, J Purswani, SM Carroll, CJ Marx BMC research notes 6, 1-8, 2013 | 50 | 2013 |
Controlled Measurement and Comparative Analysis of Cellular Components in E. coli Reveals Broad Regulatory Changes in Response to Glucose Starvation JR Houser, C Barnhart, DR Boutz, SM Carroll, A Dasgupta, JK Michener, ... PLoS computational biology 11 (8), e1004400, 2015 | 47 | 2015 |
Hopanoid-free Methylobacterium extorquens DM4 overproduces carotenoids and has widespread growth impairment AS Bradley, PK Swanson, EEL Muller, F Bringel, SM Caroll, A Pearson, ... PLoS One 12 (3), e0173323, 2017 | 24 | 2017 |
Laboratory divergence of Methylobacterium extorquens AM1 through unintended domestication and past selection for antibiotic resistance SM Carroll, KS Xue, CJ Marx BMC microbiology 14, 1-12, 2014 | 18 | 2014 |
Sign epistasis limits evolutionary trade-offs at the confluence of single-and multi-carbon metabolism in Methylobacterium extorquens AM1 SM Carroll, MC Lee, CJ Marx Evolution 68 (3), 760-771, 2014 | 16 | 2014 |
Compositions and methods for the treatment of neuronal injury G De Rienzo, R Afeyan, S Carroll, M Russell US Patent App. 16/103,200, 2019 | 15 | 2019 |
Safety, Tolerability, and Physiological Effects of AXA1665, a Novel Composition of Amino Acids, in Subjects With Child–Pugh A and B Cirrhosis MV Chakravarthy, J Neutel, S Confer, P Zhao, N Tatsuta, S Rebello, ... Clinical and Translational Gastroenterology 11 (8), e00222, 2020 | 14 | 2020 |
Compositions and methods for the treatment of liver diseases and disorders associated with one or both of hyperammonemia or muscle wasting W Comb, S Carroll, R Afeyan, M Hamill US Patent 10,682,325, 2020 | 11 | 2020 |
Parallel and Divergent Evolutionary Solutions for the Optimization of an Engineered Central Metabolism in Methylobacterium extorquens AM1 SM Carroll, LM Chubiz, D Agashe, CJ Marx Microorganisms 3 (2), 152-174, 2015 | 11 | 2015 |
Lamprey endocrinology is not ancestral JW Thornton, SM Carroll Proceedings of the National Academy of Sciences 108 (2), E5-E5, 2011 | 10 | 2011 |
Compositions and methods for the treatment of liver diseases and disorders associated with one or both of hyperammonemia or muscle wasting W Comb, S Carroll, R Afeyan, M Hamill US Patent 10,660,870, 2020 | 8 | 2020 |
Compositions and methods for the treatment of hemoglobinopathies and thalassemias S Carroll, M Russell, R Afeyan US Patent App. 17/341,716, 2021 | 1 | 2021 |
A novel composition of endogenous metabolic modulators, AXA4010, impacts adhesion, inflammation and RBC membrane deformability in preclinical models of sickle cell disease M Hamill, S Carroll, R Wani, M Russell, Z Steuert, A Nitzel, A Downey, ... Blood 134, 978, 2019 | 1 | 2019 |
Compositions and methods for the treatment of liver diseases and disorders N Daou, W Comb, A Williams, S Marukian, M Hamill, R Afeyan, S Carroll, ... US Patent App. 17/788,474, 2023 | | 2023 |