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Martine I. Abboud
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Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
TL Yeh, TM Leissing, MI Abboud, CC Thinnes, O Atasoylu, JP Holt-Martyn, ...
Chemical science 8 (11), 7651-7668, 2017
2042017
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
R Chowdhury, IKH Leung, YM Tian, MI Abboud, W Ge, C Domene, ...
Nature communications 7 (1), 12673, 2016
1282016
The road to avibactam: the first clinically useful non-β-lactam working somewhat like a β-lactam
DY Wang, MI Abboud, MS Markoulides, J Brem, CJ Schofield
Future medicinal chemistry 8 (10), 1063-1084, 2016
1262016
Interaction of avibactam with class B metallo-β-lactamases
MI Abboud, C Damblon, J Brem, N Smargiasso, P Mercuri, B Gilbert, ...
Antimicrobial agents and chemotherapy 60 (10), 5655-5662, 2016
1132016
Targeting protein–protein interactions in the HIF system
SE Wilkins, MI Abboud, RL Hancock, CJ Schofield
ChemMedChem 11 (8), 773-786, 2016
1002016
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
ME Cockman, K Lippl, YM Tian, HB Pegg, WD Figg, MI Abboud, R Heilig, ...
Elife 8, e46490, 2019
832019
NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors
GB Li, MI Abboud, J Brem, H Someya, CT Lohans, SY Yang, J Spencer, ...
Chemical Science 8 (2), 928-937, 2017
762017
Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population
E Hariri, MI Abboud, S Demirdjian, S Korfali, M Mroueh, RI Taleb
Journal of Food Composition and Analysis 42, 91-97, 2015
722015
Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells
J Walsby-Tickle, J Gannon, I Hvinden, C Bardella, MI Abboud, A Nazeer, ...
Communications biology 3 (1), 247, 2020
712020
Comparison of Verona integron-borne metallo-β-lactamase (VIM) variants reveals differences in stability and inhibition profiles
A Makena, AÖ Düzgün, J Brem, MA McDonough, AM Rydzik, MI Abboud, ...
Antimicrobial agents and chemotherapy 60 (3), 1377-1384, 2016
612016
Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate
Z Zhang, TJ Smart, H Choi, F Hardy, CT Lohans, MI Abboud, ...
Proceedings of the National Academy of Sciences 114 (18), 4667-4672, 2017
522017
In silico fragment-based design identifies subfamily B1 metallo-β-lactamase inhibitors
R Cain, J Brem, D Zollman, MA McDonough, RM Johnson, J Spencer, ...
Journal of Medicinal Chemistry 61 (3), 1255-1260, 2018
482018
Carcinogenic and neurotoxic risks of acrylamide consumed through caffeinated beverages among the lebanese population
GEZ Naous, A Merhi, MI Abboud, M Mroueh, RI Taleb
Chemosphere 208, 352-357, 2018
432018
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
S Markolovic, Q Zhuang, SE Wilkins, CD Eaton, MI Abboud, MJ Katz, ...
Nature chemical biology 14 (7), 688-695, 2018
382018
Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition
GB Li, J Brem, R Lesniak, MI Abboud, CT Lohans, IJ Clifton, SY Yang, ...
Chemical communications 53 (43), 5806-5809, 2017
342017
Normal tissue radioprotection by amifostine via Warburg-type effects
MI Koukourakis, A Giatromanolaki, CE Zois, D Kalamida, S Pouliliou, ...
Scientific reports 6 (1), 30986, 2016
332016
A diverse view of science to catalyse change
CA Urbina-Blanco, SZ Jilani, IR Speight, MJ Bojdys, T Friščić, JF Stoddart, ...
Nature Chemistry, 1-4, 2020
322020
The clinically used iron chelator deferasirox is an inhibitor of epigenetic JumonjiC domain-containing histone demethylases
M Roatsch, I Hoffmann, MI Abboud, RL Hancock, H Tarhonskaya, KF Hsu, ...
ACS Chemical Biology 14 (8), 1737-1750, 2019
312019
Cyclobutanone mimics of intermediates in metallo‐β‐lactamase catalysis
MI Abboud, M Kosmopoulou, AP Krismanich, JW Johnson, P Hinchliffe, ...
Chemistry–A European Journal 24 (22), 5734-5737, 2018
312018
2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2
MI Abboud, TE McAllister, IKH Leung, R Chowdhury, C Jorgensen, ...
Chemical communications 54 (25), 3130-3133, 2018
312018
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