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Martine I. Abboud
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Year
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
TL Yeh, TM Leissing, MI Abboud, CC Thinnes, O Atasoylu, JP Holt-Martyn, ...
Chemical science 8 (11), 7651-7668, 2017
2242017
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
R Chowdhury, IKH Leung, YM Tian, MI Abboud, W Ge, C Domene, ...
Nature communications 7 (1), 12673, 2016
1472016
The road to avibactam: the first clinically useful non-β-lactam working somewhat like a β-lactam
DY Wang, MI Abboud, MS Markoulides, J Brem, CJ Schofield
Future medicinal chemistry 8 (10), 1063-1084, 2016
1332016
Interaction of avibactam with class B metallo-β-lactamases
MI Abboud, C Damblon, J Brem, N Smargiasso, P Mercuri, B Gilbert, ...
Antimicrobial agents and chemotherapy 60 (10), 5655-5662, 2016
1192016
Targeting protein–protein interactions in the HIF system
SE Wilkins, MI Abboud, RL Hancock, CJ Schofield
ChemMedChem 11 (8), 773-786, 2016
1062016
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates
ME Cockman, K Lippl, YM Tian, HB Pegg, WD Figg, MI Abboud, R Heilig, ...
Elife 8, e46490, 2019
952019
Anion-exchange chromatography mass spectrometry provides extensive coverage of primary metabolic pathways revealing altered metabolism in IDH1 mutant cells
J Walsby-Tickle, J Gannon, I Hvinden, C Bardella, MI Abboud, A Nazeer, ...
Communications biology 3 (1), 247, 2020
812020
NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors
GB Li, MI Abboud, J Brem, H Someya, CT Lohans, SY Yang, J Spencer, ...
Chemical Science 8 (2), 928-937, 2017
782017
Carcinogenic and neurotoxic risks of acrylamide and heavy metals from potato and corn chips consumed by the Lebanese population
E Hariri, MI Abboud, S Demirdjian, S Korfali, M Mroueh, RI Taleb
Journal of Food Composition and Analysis 42, 91-97, 2015
762015
Comparison of Verona integron-borne metallo-β-lactamase (VIM) variants reveals differences in stability and inhibition profiles
A Makena, AÖ Düzgün, J Brem, MA McDonough, AM Rydzik, MI Abboud, ...
Antimicrobial agents and chemotherapy 60 (3), 1377-1384, 2016
682016
Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate
Z Zhang, TJ Smart, H Choi, F Hardy, CT Lohans, MI Abboud, ...
Proceedings of the National Academy of Sciences 114 (18), 4667-4672, 2017
582017
In silico fragment-based design identifies subfamily B1 metallo-β-lactamase inhibitors
R Cain, J Brem, D Zollman, MA McDonough, RM Johnson, J Spencer, ...
Journal of Medicinal Chemistry 61 (3), 1255-1260, 2018
522018
Carcinogenic and neurotoxic risks of acrylamide consumed through caffeinated beverages among the lebanese population
GEZ Naous, A Merhi, MI Abboud, M Mroueh, RI Taleb
Chemosphere 208, 352-357, 2018
472018
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
S Markolovic, Q Zhuang, SE Wilkins, CD Eaton, MI Abboud, MJ Katz, ...
Nature chemical biology 14 (7), 688-695, 2018
442018
JMJD6 is a druggable oxygenase that regulates AR-V7 expression in prostate cancer
A Paschalis, J Welti, AJ Neeb, W Yuan, I Figueiredo, R Pereira, A Ferreira, ...
Cancer research 81 (4), 1087-1100, 2022
392022
A diverse view of science to catalyse change
CA Urbina-Blanco, SZ Jilani, IR Speight, MJ Bojdys, T Friščić, JF Stoddart, ...
Nature Chemistry, 1-4, 2020
362020
2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2
MI Abboud, TE McAllister, IKH Leung, R Chowdhury, C Jorgensen, ...
Chemical Communications 54 (25), 3130-3133, 2018
362018
Normal tissue radioprotection by amifostine via Warburg-type effects
MI Koukourakis, A Giatromanolaki, CE Zois, D Kalamida, S Pouliliou, ...
Scientific reports 6 (1), 30986, 2016
362016
Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors
R Reinbold, IC Hvinden, P Rabe, RA Herold, A Finch, J Wood, M Morgan, ...
Nature Communications 13 (1), 4785, 2022
352022
Non-competitive cyclic peptides for targeting enzyme–substrate complexes
TE McAllister, TL Yeh, MI Abboud, IKH Leung, ES Hookway, ONF King, ...
Chemical Science 9 (20), 4569-4578, 2018
342018
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Articles 1–20