| A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4597 | 2020 |
| A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p J Taunton, CA Hassig, SL Schreiber Science 272 (5260), 408-411, 1996 | 2572 | 1996 |
| Phase separation of signaling molecules promotes T cell receptor signal transduction X Su, JA Ditlev, E Hui, W Xing, S Banjade, J Okrut, DS King, J Taunton, ... Science 352 (6285), 595-599, 2016 | 1087 | 2016 |
| RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation PP Roux, D Shahbazian, H Vu, MK Holz, MS Cohen, J Taunton, ... Journal of Biological Chemistry 282 (19), 14056-14064, 2007 | 893 | 2007 |
| The promise and peril of chemical probes CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ... Nature Chemical Biology 11 (8), 536-541, 2015 | 854 | 2015 |
| Structural bioinformatics-based design of selective, irreversible kinase inhibitors MS Cohen, C Zhang, KM Shokat, J Taunton Science 308 (5726), 1318-1321, 2005 | 722 | 2005 |
| The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity D Shahbazian, PP Roux, V Mieulet, MS Cohen, B Raught, J Taunton, ... The EMBO journal 25 (12), 2781-2791, 2006 | 687 | 2006 |
| High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases F Chen, SM Pruett-Miller, Y Huang, M Gjoka, K Duda, J Taunton, ... Nature methods 8 (9), 753-755, 2011 | 659 | 2011 |
| Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles IM Serafimova, MA Pufall, S Krishnan, K Duda, MS Cohen, RL Maglathlin, ... Nature chemical biology 8 (5), 471-476, 2012 | 574 | 2012 |
| Actin-Dependent Propulsion of Endosomes and Lysosomes by Recruitment of N-Wasp✪ J Taunton, BA Rowning, ML Coughlin, M Wu, RT Moon, TJ Mitchison, ... The Journal of cell biology 148 (3), 519-530, 2000 | 516 | 2000 |
| Prolonged and tunable residence time using reversible covalent kinase inhibitors JM Bradshaw, JM McFarland, VO Paavilainen, A Bisconte, D Tam, ... Nature chemical biology 11 (7), 525-531, 2015 | 434 | 2015 |
| Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains MA Puthenveedu, B Lauffer, P Temkin, R Vistein, P Carlton, K Thorn, ... Cell 143 (5), 761-773, 2010 | 369 | 2010 |
| Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway SW Kang, NS Rane, SJ Kim, JL Garrison, J Taunton, RS Hegde Cell 127 (5), 999-1013, 2006 | 332 | 2006 |
| Broad-spectrum kinase profiling in live cells with lysine-targeted sulfonyl fluoride probes Q Zhao, X Ouyang, X Wan, KS Gajiwala, JC Kath, LH Jones, ... Journal of the American Chemical Society 139 (2), 680-685, 2017 | 330 | 2017 |
| Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload S Oyadomari, C Yun, EA Fisher, N Kreglinger, G Kreibich, M Oyadomari, ... Cell 126 (4), 727-739, 2006 | 307 | 2006 |
| Comparative flavivirus-host protein interaction mapping reveals mechanisms of dengue and Zika virus pathogenesis PS Shah, N Link, GM Jang, PP Sharp, T Zhu, DL Swaney, JR Johnson, ... Cell 175 (7), 1931-1945. e18, 2018 | 290 | 2018 |
| Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis S Krishnan, RM Miller, B Tian, RD Mullins, MP Jacobson, J Taunton Journal of the American Chemical Society 136 (36), 12624-12630, 2014 | 274 | 2014 |
| Covalent docking of large libraries for the discovery of chemical probes N London, RM Miller, JJ Irwin, O Eidam, L Gibold, R Bonnet, BK Shoichet, ... Biophysical Journal 106 (2), 264a, 2014 | 267 | 2014 |
| The Role of p58IPK in Protecting the Stressed Endoplasmic Reticulum DT Rutkowski, SW Kang, AG Goodman, JL Garrison, J Taunton, MG Katze, ... Molecular biology of the cell 18 (9), 3681-3691, 2007 | 253 | 2007 |
| RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells U Doehn, C Hauge, SR Frank, CJ Jensen, K Duda, JV Nielsen, ... Molecular cell 35 (4), 511-522, 2009 | 251 | 2009 |
