High throughput fluorescence polarization: a homogeneous alternative to radioligand binding for cell surface receptors M Allen, J Reeves, G Mellor Journal of biomolecular screening 5 (2), 63-69, 2000 | 126 | 2000 |
The discovery of GSK221149A: a potent and selective oxytocin antagonist J Liddle, MJ Allen, AD Borthwick, DP Brooks, DE Davies, RM Edwards, ... Bioorganic & medicinal chemistry letters 18 (1), 90-94, 2008 | 101 | 2008 |
2, 5-Diketopiperazines as potent and selective oxytocin antagonists 1: Identification, stereochemistry and initial SAR PG Wyatt, MJ Allen, AD Borthwick, DE Davies, AM Exall, RJD Hatley, ... Bioorganic & medicinal chemistry letters 15 (10), 2579-2582, 2005 | 89 | 2005 |
Paracrine oxytocin and estradiol demonstrate a spatial increase in human intrauterine tissues with labor AM Blanks, M Vatish, MJ Allen, G Ladds, NCJ de Wit, DM Slater, ... The Journal of Clinical Endocrinology & Metabolism 88 (7), 3392-3400, 2003 | 75 | 2003 |
2, 5-Diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 2. Synthesis, chirality, and pharmacokinetics AD Borthwick, DE Davies, AM Exall, DG Livermore, SL Sollis, F Nerozzi, ... Journal of medicinal chemistry 48 (22), 6956-6969, 2005 | 72 | 2005 |
Pyridyl-2, 5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency AD Borthwick, J Liddle, DE Davies, AM Exall, C Hamlett, DM Hickey, ... Journal of Medicinal Chemistry 55 (2), 783-796, 2012 | 67 | 2012 |
2, 5-Diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 3. Synthesis, pharmacokinetics, and in vivo potency AD Borthwick, DE Davies, AM Exall, RJD Hatley, JA Hughes, WR Irving, ... Journal of medicinal chemistry 49 (14), 4159-4170, 2006 | 56 | 2006 |
Structure–activity relationship investigations of a potent and selective benzodiazepine oxytocin antagonist PG Wyatt, MJ Allen, J Chilcott, G Hickin, ND Miller, PM Woollard Bioorganic & medicinal chemistry letters 11 (10), 1301-1305, 2001 | 56 | 2001 |
Identification of potent and selective oxytocin antagonists. Part 2: further investigation of benzofuran derivatives PG Wyatt, MJ Allen, J Chilcott, CJ Gardner, DG Livermore, JE Mordaunt, ... Bioorganic & medicinal chemistry letters 12 (10), 1405-1411, 2002 | 55 | 2002 |
Identification of potent and selective oxytocin antagonists. Part 1: indole and benzofuran derivatives PG Wyatt, MJ Allen, J Chilcott, A Foster, DG Livermore, JE Mordaunt, ... Bioorganic & medicinal chemistry letters 12 (10), 1399-1404, 2002 | 50 | 2002 |
A modelling tool for capacity planning in acute and community stroke services T Monks, D Worthington, M Allen, M Pitt, K Stein, MA James BMC health services research 16, 1-8, 2016 | 48 | 2016 |
Right cot, right place, right time: improving the design and organisation of neonatal care networks–a computer simulation study M Allen, A Spencer, A Gibson, J Matthews, A Allwood, S Prosser, M Pitt | 48 | 2015 |
Not all waits are equal: an exploratory investigation of emergency care patient pathways D Swancutt, S Joel-Edgar, M Allen, D Thomas, H Brant, J Benger, R Byng, ... BMC health services research 17 (1), 1-10, 2017 | 45 | 2017 |
Involving patients and the public in healthcare operational research—the challenges and opportunities M Pearson, T Monks, A Gibson, M Allen, A Komashie, A Fordyce, ... Operations Research for Health Care 2 (4), 86-89, 2013 | 41 | 2013 |
Use of a novel and highly selective oxytocin receptor antagonist to characterize uterine contractions in the rat GP McCafferty, MA Pullen, C Wu, RM Edwards, MJ Allen, PM Woollard, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007 | 41 | 2007 |
Maximising access to thrombectomy services for stroke in England: a modelling study M Allen, K Pearn, M James, GA Ford, P White, AG Rudd, P McMeekin, ... European stroke journal 4 (1), 39-49, 2019 | 37 | 2019 |
Spontaneous contractions of myometrium from humans, non-human primate and rodents are sensitive to selective oxytocin receptor antagonism in vitro RJ Wilson, MJ Allen, M Nandi, H Giles, S Thornton British Journal of Obstetrics and Gynaecology 108 (9), 960-966, 2001 | 36 | 2001 |
A simulation modelling toolkit for organising outpatient dialysis services during the COVID-19 pandemic M Allen, A Bhanji, J Willemsen, S Dudfield, S Logan, T Monks PLoS One 15 (8), e0237628, 2020 | 29 | 2020 |
A framework to accelerate simulation studies of hyperacute stroke systems T Monks, DJ Van der Zee, MMH Lahr, M Allen, K Pearn, MA James, ... Operations Research for Health Care 15, 57-67, 2017 | 25 | 2017 |
How can frontline expertise and new models of care best contribute to safely reducing avoidable acute admissions? A mixed-methods study of four acute hospitals J Pinkney, S Rance, J Benger, H Brant, S Joel-Edgar, D Swancutt, ... National Institute for Health Research, 2016 | 20 | 2016 |