Critical role of both p27KIP1and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in … E Di Gennaro, M Barbarino, F Bruzzese, S De Lorenzo, M Caraglia, ... Journal of cellular physiology 195 (1), 139-150, 2003 | 185 | 2003 |
Novel camptothecin analogue (gimatecan)‐containing liposomes prepared by the ethanol injection method P Stano, S Bufali, C Pisano, F Bucci, M Barbarino, M Santaniello, ... Journal of liposome research 14 (1-2), 87-109, 2004 | 138 | 2004 |
CRH inhibits cell growth of human endometrial adenocarcinoma cells via CRH-receptor 1-mediated activation of cAMP-PKA pathway G Graziani, L Tentori, I Portarena, M Barbarino, G Tringali, G Pozzoli, ... Endocrinology 143 (3), 807-813, 2002 | 95 | 2002 |
Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors S Dallavalle, R Cincinelli, R Nannei, L Merlini, G Morini, S Penco, ... European journal of medicinal chemistry 44 (5), 1900-1912, 2009 | 81 | 2009 |
Synthesis and evaluation of new Hsp90 inhibitors based on a 1, 4, 5-trisubstituted 1, 2, 3-triazole scaffold M Taddei, S Ferrini, L Giannotti, M Corsi, F Manetti, G Giannini, L Vesci, ... Journal of Medicinal Chemistry 57 (6), 2258-2274, 2014 | 75 | 2014 |
MicroRNA-34a and MicroRNA-181a mediate visfatin-induced apoptosis and oxidative stress via NF-κB pathway in human osteoarthritic chondrocytes S Cheleschi, S Tenti, N Mondanelli, C Corallo, M Barbarino, S Giannotti, ... Cells 8 (8), 874, 2019 | 68 | 2019 |
Inhibition of telomerase increases resistance of melanoma cells to temozolomide, but not to temozolomide combined with poly (adp-ribose) polymerase inhibitor L Tentori, I Portarena, M Barbarino, A Balduzzi, L Levati, M Vergati, ... Molecular pharmacology 63 (1), 192-202, 2003 | 58 | 2003 |
ST7612AA1, a thioacetate-ω (γ-lactam carboxamide) derivative selected from a novel generation of oral HDAC inhibitors G Giannini, L Vesci, G Battistuzzi, D Vignola, FM Milazzo, MB Guglielmi, ... Journal of Medicinal Chemistry 57 (20), 8358-8377, 2014 | 57 | 2014 |
Assessment of the carcinogenicity of carbon nanotubes in the respiratory system M Barbarino, A Giordano Cancers 13 (6), 1318, 2021 | 47 | 2021 |
Novel 3, 4-isoxazolediamides as potent inhibitors of chaperone heat shock protein 90 R Baruchello, D Simoni, G Grisolia, G Barbato, P Marchetti, R Rondanin, ... Journal of medicinal chemistry 54 (24), 8592-8604, 2011 | 44 | 2011 |
Isoxazolo (aza) naphthoquinones: A new class of cytotoxic Hsp90 inhibitors A Bargiotti, L Musso, S Dallavalle, L Merlini, G Gallo, A Ciacci, G Giannini, ... European journal of medicinal chemistry 53, 64-75, 2012 | 42 | 2012 |
MicroRNA mediate visfatin and resistin induction of oxidative stress in human osteoarthritic synovial fibroblasts via NF-κB pathway S Cheleschi, I Gallo, M Barbarino, S Giannotti, N Mondanelli, A Giordano, ... International Journal of Molecular Sciences 20 (20), 5200, 2019 | 40 | 2019 |
Novel PARP-1 inhibitors based on a 2-propanoyl-3H-quinazolin-4-one scaffold G Giannini, G Battistuzzi, L Vesci, FM Milazzo, F De Paolis, M Barbarino, ... Bioorganic & medicinal chemistry letters 24 (2), 462-466, 2014 | 40 | 2014 |
ω-Alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: A study of chain-length and stereochemical dependence S Hanessian, L Auzzas, G Giannini, M Marzi, W Cabri, M Barbarino, ... Bioorganic & medicinal chemistry letters 17 (22), 6261-6265, 2007 | 37 | 2007 |
ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, upregulates p27Kip1 inducing G1 arrest and enhancing the antitumor effect of interferon a A Budillon, E Di Gennaro, M Barbarino, F Bruzzese, S De Lorenzo, ... Proc Am Assoc Cancer Res 41 (773), A4910, 2000 | 37 | 2000 |
Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA … V Zuco, C Zanchi, C Lanzi, GL Beretta, R Supino, C Pisano, M Barbarino, ... Neoplasia 7 (7), 667-677, 2005 | 33 | 2005 |
TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration GM Tosi, G Neri, E Caldi, F Fusco, T Bacci, A Tarantello, E Nuti, ... Scientific Reports 8 (1), 8053, 2018 | 32 | 2018 |
Mesothelioma malignancy and the microenvironment: molecular mechanisms F Cersosimo, M Barbarino, S Lonardi, W Vermi, A Giordano, C Bellan, ... Cancers 13 (22), 5664, 2021 | 31 | 2021 |
Nanoparticle‐biomolecular corona: A new approach for the early detection of non‐small‐cell lung cancer M Di Domenico, D Pozzi, S Palchetti, L Digiacomo, R Iorio, C Astarita, ... Journal of Cellular Physiology 234 (6), 9378-9386, 2019 | 30 | 2019 |
Metabolic Approach to the Enhancement of Antitumor Effect of Chemotherapy: a Key Role of Acetyl-l-Carnitine C Pisano, L Vesci, FM Milazzo, MB Guglielmi, R Foderą, M Barbarino, ... Clinical Cancer Research 16 (15), 3944-3953, 2010 | 29 | 2010 |