Mariane B Melo
Mariane B Melo
Senior Director, Vaccines R&D
Verified email at - Homepage
Cited by
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Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery
L Tang, Y Zheng, MB Melo, L Mabardi, AP Castańo, YQ Xie, N Li, ...
Nature biotechnology 36 (8), 707-716, 2018
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination
HH Tam, MB Melo, M Kang, JM Pelet, VM Ruda, MH Foley, JK Hu, ...
Proceedings of the National Academy of Sciences 113 (43), E6639-E6648, 2016
Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants
MC Hanson, MP Crespo, W Abraham, KD Moynihan, GL Szeto, SH Chen, ...
The Journal of clinical investigation 125 (6), 2532-2546, 2015
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
KM Cirelli, DG Carnathan, B Nogal, JT Martin, OL Rodriguez, ...
Cell 177 (5), 1153-1171. e28, 2019
Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice
WA Andrade, M do Carmo Souza, E Ramos-Martinez, K Nagpal, ...
Cell host & microbe 13 (1), 42-53, 2013
The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response
W Niedelman, DA Gold, EE Rosowski, JK Sprokholt, D Lim, ...
PLoS pathogens 8 (6), e1002784, 2012
The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease
C Junqueira, B Caetano, DC Bartholomeu, MB Melo, C Ropert, ...
Expert reviews in molecular medicine 12, e29, 2010
Toxoplasma gondii effectors are master regulators of the inflammatory response
MB Melo, KDC Jensen, JPJ Saeij
Trends in parasitology 27 (11), 487-495, 2011
Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii
G Gorfu, KM Cirelli, MB Melo, K Mayer-Barber, D Crown, BH Koller, ...
MBio 5 (1), 10.1128/mbio. 01117-13, 2014
Engineered immunogen binding to alum adjuvant enhances humoral immunity
TJ Moyer, Y Kato, W Abraham, JYH Chang, DW Kulp, N Watson, ...
Nature Medicine 26 (3), 430-440, 2020
STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity
EL Dane, A Belessiotis-Richards, C Backlund, J Wang, K Hidaka, ...
Nature Materials 21 (6), 710-720, 2022
Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity
S Minot, MB Melo, F Li, D Lu, W Niedelman, SS Levine, JPJ Saeij
Proceedings of the National Academy of Sciences 109 (33), 13458-13463, 2012
Transcriptional analysis of murine macrophages infected with different Toxoplasma strains identifies novel regulation of host signaling pathways
MB Melo, QP Nguyen, C Cordeiro, MA Hassan, N Yang, R McKell, ...
PLoS Pathog 9 (12), e1003779, 2013
Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi
BC Caetano, BB Carmo, MB Melo, A Cerny, SL dos Santos, ...
The Journal of Immunology 187 (4), 1903-1911, 2011
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi
DC Bartholomeu, C Ropert, MB Melo, P Parroche, CF Junqueira, ...
The Journal of Immunology 181 (2), 1333-1344, 2008
Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination
KDC Jensen, A Camejo, MB Melo, C Cordeiro, L Julien, GM Grotenbreg, ...
MBio 6 (2), 10.1128/mbio. 02280-14, 2015
UNC93B1 Mediates Host Resistance to Infection with Toxoplasma gondii
MB Melo, P Kasperkovitz, A Cerny, S Könen-Waisman, EA Kurt-Jones, ...
PLoS pathogens 6 (8), e1001071, 2010
Enhancing humoral responses against HIV envelope trimers via nanoparticle delivery with stabilized synthetic liposomes
T Tokatlian, DW Kulp, AA Mutafyan, CA Jones, S Menis, E Georgeson, ...
Scientific Reports 8 (1), 16527, 2018
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity
Y Agarwal, LE Milling, JYH Chang, L Santollani, A Sheen, EA Lutz, ...
Nature biomedical engineering 6 (2), 129-143, 2022
Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles
YSS Yang, KD Moynihan, A Bekdemir, TM Dichwalkar, MM Noh, ...
Biomaterials science 7 (1), 113-124, 2019
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