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Mariane B Melo
Mariane B Melo
Senior Director, Vaccines R&D
Verified email at mit.edu - Homepage
Title
Cited by
Cited by
Year
Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery
L Tang, Y Zheng, MB Melo, L Mabardi, AP Castańo, YQ Xie, N Li, ...
Nature biotechnology 36 (8), 707-716, 2018
5242018
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination
HH Tam, MB Melo, M Kang, JM Pelet, VM Ruda, MH Foley, JK Hu, ...
Proceedings of the National Academy of Sciences 113 (43), E6639-E6648, 2016
3732016
Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants
MC Hanson, MP Crespo, W Abraham, KD Moynihan, GL Szeto, SH Chen, ...
The Journal of clinical investigation 125 (6), 2532-2546, 2015
3652015
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
KM Cirelli, DG Carnathan, B Nogal, JT Martin, OL Rodriguez, ...
Cell 177 (5), 1153-1171. e28, 2019
3152019
Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice
WA Andrade, M do Carmo Souza, E Ramos-Martinez, K Nagpal, ...
Cell host & microbe 13 (1), 42-53, 2013
2552013
The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response
W Niedelman, DA Gold, EE Rosowski, JK Sprokholt, D Lim, ...
PLoS pathogens 8 (6), e1002784, 2012
2532012
The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease
C Junqueira, B Caetano, DC Bartholomeu, MB Melo, C Ropert, ...
Expert reviews in molecular medicine 12, e29, 2010
2522010
Toxoplasma gondii effectors are master regulators of the inflammatory response
MB Melo, KDC Jensen, JPJ Saeij
Trends in parasitology 27 (11), 487-495, 2011
2392011
Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii
G Gorfu, KM Cirelli, MB Melo, K Mayer-Barber, D Crown, BH Koller, ...
MBio 5 (1), 10.1128/mbio. 01117-13, 2014
2342014
Engineered immunogen binding to alum adjuvant enhances humoral immunity
TJ Moyer, Y Kato, W Abraham, JYH Chang, DW Kulp, N Watson, ...
Nature Medicine 26 (3), 430-440, 2020
2082020
STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity
EL Dane, A Belessiotis-Richards, C Backlund, J Wang, K Hidaka, ...
Nature Materials 21 (6), 710-720, 2022
1282022
Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity
S Minot, MB Melo, F Li, D Lu, W Niedelman, SS Levine, JPJ Saeij
Proceedings of the National Academy of Sciences 109 (33), 13458-13463, 2012
1132012
Transcriptional analysis of murine macrophages infected with different Toxoplasma strains identifies novel regulation of host signaling pathways
MB Melo, QP Nguyen, C Cordeiro, MA Hassan, N Yang, R McKell, ...
PLoS Pathog 9 (12), e1003779, 2013
1092013
Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi
BC Caetano, BB Carmo, MB Melo, A Cerny, SL dos Santos, ...
The Journal of Immunology 187 (4), 1903-1911, 2011
962011
Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi
DC Bartholomeu, C Ropert, MB Melo, P Parroche, CF Junqueira, ...
The Journal of Immunology 181 (2), 1333-1344, 2008
882008
Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination
KDC Jensen, A Camejo, MB Melo, C Cordeiro, L Julien, GM Grotenbreg, ...
MBio 6 (2), 10.1128/mbio. 02280-14, 2015
872015
UNC93B1 Mediates Host Resistance to Infection with Toxoplasma gondii
MB Melo, P Kasperkovitz, A Cerny, S Könen-Waisman, EA Kurt-Jones, ...
PLoS pathogens 6 (8), e1001071, 2010
872010
Enhancing humoral responses against HIV envelope trimers via nanoparticle delivery with stabilized synthetic liposomes
T Tokatlian, DW Kulp, AA Mutafyan, CA Jones, S Menis, E Georgeson, ...
Scientific Reports 8 (1), 16527, 2018
802018
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity
Y Agarwal, LE Milling, JYH Chang, L Santollani, A Sheen, EA Lutz, ...
Nature biomedical engineering 6 (2), 129-143, 2022
772022
Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles
YSS Yang, KD Moynihan, A Bekdemir, TM Dichwalkar, MM Noh, ...
Biomaterials science 7 (1), 113-124, 2019
772019
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