X-ROS signaling: rapid mechano-chemo transduction in heart BL Prosser, CW Ward, WJ Lederer Science 333 (6048), 1440-1445, 2011 | 598 | 2011 |
Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes P Robison, MA Caporizzo, H Ahmadzadeh, AI Bogush, CY Chen, ... Science 352 (6284), aaf0659, 2016 | 318 | 2016 |
Microtubules underlie dysfunction in duchenne muscular dystrophy RJ Khairallah, G Shi, F Sbrana, BL Prosser, C Borroto, MJ Mazaitis, ... Science signaling 5 (236), ra56-ra56, 2012 | 296 | 2012 |
Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell-cycle arrest S Cho, M Vashisth, A Abbas, S Majkut, K Vogel, Y Xia, IL Ivanovska, ... Developmental cell 49 (6), 920-935. e5, 2019 | 262 | 2019 |
Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure CY Chen, MA Caporizzo, K Bedi, A Vite, AI Bogush, P Robison, JG Heffler, ... Nature medicine 24 (8), 1225-1233, 2018 | 239 | 2018 |
Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle JP Kerr, P Robison, G Shi, AI Bogush, AM Kempema, JK Hexum, ... Nature communications 6 (1), 8526, 2015 | 219 | 2015 |
X-ROS signaling in the heart and skeletal muscle: stretch-dependent local ROS regulates [Ca2+] i BL Prosser, RJ Khairallah, AP Ziman, CW Ward, WJ Lederer Journal of molecular and cellular cardiology 58, 172-181, 2013 | 155 | 2013 |
S100A1 and calmodulin compete for the same binding site on ryanodine receptor NT Wright, BL Prosser, KM Varney, DB Zimmer, MF Schneider, DJ Weber Journal of Biological Chemistry 283 (39), 26676-26683, 2008 | 143 | 2008 |
S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling BL Prosser, NT Wright, EO Hernandez-Ochoa, KM Varney, Y Liu, ... Journal of Biological Chemistry 283 (8), 5046-5057, 2008 | 124 | 2008 |
Cardiac microtubules in health and heart disease MA Caporizzo, CY Chen, BL Prosser Experimental Biology and Medicine 244 (15), 1255-1272, 2019 | 110 | 2019 |
Mechanical stretch-induced activation of ROS/RNS signaling in striated muscle CW Ward, BL Prosser, WJ Lederer Antioxidants & redox signaling 20 (6), 929-936, 2014 | 104 | 2014 |
A balance between intermediate filaments and microtubules maintains nuclear architecture in the cardiomyocyte J Heffler, PP Shah, P Robison, S Phyo, K Veliz, K Uchida, A Bogush, ... Circulation research 126 (3), e10-e26, 2020 | 102 | 2020 |
Contractile function during angiotensin-II activation: increased Nox2 activity modulates cardiac calcium handling via phospholamban phosphorylation M Zhang, BL Prosser, MA Bamboye, ANS Gondim, CX Santos, D Martin, ... Journal of the American College of Cardiology 66 (3), 261-272, 2015 | 99 | 2015 |
MIRO-1 determines mitochondrial shape transition upon GPCR activation and Ca2+ stress N Nemani, E Carvalho, D Tomar, Z Dong, A Ketschek, SL Breves, F Jaņa, ... Cell reports 23 (4), 1005-1019, 2018 | 98 | 2018 |
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes PP Shah, W Lv, JH Rhoades, A Poleshko, D Abbey, MA Caporizzo, ... Cell Stem Cell 28 (5), 938-954. e9, 2021 | 95 | 2021 |
Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling MJ Previs, BL Prosser, JY Mun, SB Previs, J Gulick, K Lee, J Robbins, ... Science advances 1 (1), e1400205, 2015 | 89 | 2015 |
Microtubules increase diastolic stiffness in failing human cardiomyocytes and myocardium MA Caporizzo, CY Chen, K Bedi, KB Margulies, BL Prosser Circulation 141 (11), 902-915, 2020 | 85 | 2020 |
Microtubules orchestrate local translation to enable cardiac growth EA Scarborough, K Uchida, M Vogel, N Erlitzki, M Iyer, SA Phyo, ... Nature communications 12 (1), 1547, 2021 | 78 | 2021 |
X-ROS signalling is enhanced and graded by cyclic cardiomyocyte stretch BL Prosser, CW Ward, WJ Lederer Cardiovascular research 98 (2), 307-314, 2013 | 77 | 2013 |
Assessing the landscape of STXBP1-related disorders in 534 individuals J Xian, S Parthasarathy, SM Ruggiero, G Balagura, E Fitch, K Helbig, ... Brain 145 (5), 1668-1683, 2022 | 76 | 2022 |