Strategies to address low drug solubility in discovery and development HD Williams, NL Trevaskis, SA Charman, RM Shanker, WN Charman, ... Pharmacological reviews 65 (1), 315-499, 2013 | 1726 | 2013 |
Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and ‘self-microemulsifying’drug delivery systems CW Pouton European journal of pharmaceutical sciences 11, S93-S98, 2000 | 1635 | 2000 |
Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system CW Pouton European journal of pharmaceutical sciences 29 (3-4), 278-287, 2006 | 1610 | 2006 |
Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies CW Pouton, CJH Porter Advanced drug delivery reviews 60 (6), 625-637, 2008 | 1085 | 2008 |
Formulation of self-emulsifying drug delivery systems CW Pouton Advanced drug delivery reviews 25 (1), 47-58, 1997 | 917 | 1997 |
Enhancing intestinal drug solubilisation using lipid-based delivery systems CJH Porter, CW Pouton, JF Cuine, WN Charman Advanced drug delivery reviews 60 (6), 673-691, 2008 | 858 | 2008 |
Key issues in non-viral gene delivery CW Pouton, LW Seymour Advanced drug delivery reviews 46 (1-3), 187-203, 2001 | 740 | 2001 |
The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation. RD Cone, D Lu, S Koppula, DI Vage, H Klungland, B Boston, W Chen, ... Recent progress in hormone research 51, 287-317; discussion 318, 1996 | 733 | 1996 |
Self-emulsifying drug delivery systems: formulation and biopharmaceutic evaluation of an investigational lipophilic compound SA Charman, WN Charman, MC Rogge, TD Wilson, FJ Dutko, CW Pouton Pharmaceutical research 9, 87-93, 1992 | 631 | 1992 |
Biosynthetic polyhydroxyalkanoates and their potential in drug delivery CW Pouton, S Akhtar Advanced Drug Delivery Reviews 18 (2), 133-162, 1996 | 543 | 1996 |
NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes DA Elliott, SR Braam, K Koutsis, ES Ng, R Jenny, EL Lagerqvist, C Biben, ... Nature methods 8 (12), 1037-1040, 2011 | 519 | 2011 |
Self-emulsifying drug delivery systems: assessment of the efficiency of emulsification CW Pouton International journal of pharmaceutics 27 (2-3), 335-348, 1985 | 416 | 1985 |
50 years of oral lipid-based formulations: provenance, progress and future perspectives OM Feeney, MF Crum, CL McEvoy, NL Trevaskis, HD Williams, ... Advanced drug delivery reviews 101, 167-194, 2016 | 391 | 2016 |
Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility DB Warren, H Benameur, CJH Porter, CW Pouton Journal of drug targeting 18 (10), 704-731, 2010 | 387 | 2010 |
Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids CW Pouton, P Lucas, BJ Thomas, AN Uduehi, DA Milroy, SH Moss Journal of controlled release 53 (1-3), 289-299, 1998 | 332 | 1998 |
Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination CP Le, CJ Nowell, C Kim-Fuchs, E Botteri, JG Hiller, H Ismail, ... Nature communications 7 (1), 10634, 2016 | 307 | 2016 |
Targeted delivery to the nucleus CW Pouton, KM Wagstaff, DM Roth, GW Moseley, DA Jans Advanced drug delivery reviews 59 (8), 698-717, 2007 | 304 | 2007 |
Influence of lipolysis on drug absorption from the gastro-intestinal tract KJ MacGregor, JK Embleton, JE Lacy, EA Perry, LJ Solomon, H Seager, ... Advanced drug Delivery reviews 25 (1), 33-46, 1997 | 295 | 1997 |
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a … HD Williams, P Sassene, K Kleberg, JC Bakala-N'Goma, M Calderone, ... Journal of pharmaceutical sciences 101 (9), 3360-3380, 2012 | 271 | 2012 |
Embryonic stem cells as a source of models for drug discovery CW Pouton, JM Haynes Nature Reviews Drug Discovery 6 (8), 605-616, 2007 | 244 | 2007 |