Expanding chemical biology of 2-oxoglutarate oxygenases C Loenarz, CJ Schofield Nature chemical biology 4 (3), 152-156, 2008 | 588 | 2008 |
Codon optimization can improve expression of human genes in Escherichia coli: A multi-gene study NA Burgess-Brown, S Sharma, F Sobott, C Loenarz, U Oppermann, ... Protein expression and purification 59 (1), 94-102, 2008 | 456 | 2008 |
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α PJ Pollard, C Loenarz, DR Mole, MA McDonough, JM Gleadle, ... Biochemical Journal 416 (3), 387-394, 2008 | 343 | 2008 |
Structural studies on human 2-oxoglutarate dependent oxygenases MA McDonough, C Loenarz, R Chowdhury, IJ Clifton, CJ Schofield Current opinion in structural biology 20 (6), 659-672, 2010 | 341 | 2010 |
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases C Loenarz, CJ Schofield Trends in biochemical sciences 36 (1), 7-18, 2011 | 328 | 2011 |
The hypoxia‐inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens C Loenarz, ML Coleman, A Boleininger, B Schierwater, PWH Holland, ... EMBO reports 12 (1), 63-70, 2011 | 290 | 2011 |
Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases R Chowdhury, MA McDonough, J Mecinović, C Loenarz, E Flashman, ... Structure 17 (7), 981-989, 2009 | 257 | 2009 |
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase C Loenarz, W Ge, ML Coleman, NR Rose, CDO Cooper, RJ Klose, ... Human molecular genetics 19 (2), 217-222, 2010 | 192 | 2010 |
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans W Ge, A Wolf, T Feng, C Ho, A Zayer, N Granatino, ME Cockman, ... Nature chemical biology 8 (12), 960-962, 2012 | 188 | 2012 |
Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family L Hillringhaus, WW Yue, NR Rose, SS Ng, C Gileadi, C Loenarz, SH Bello, ... Journal of Biological Chemistry 286 (48), 41616-41625, 2011 | 186 | 2011 |
Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α) A Thalhammer, Z Bencokova, R Poole, C Loenarz, J Adam, L O'Flaherty, ... PloS one 6 (1), e16210, 2011 | 171 | 2011 |
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy C Loenarz, R Sekirnik, A Thalhammer, W Ge, E Spivakovsky, ... Proceedings of the National Academy of Sciences 111 (11), 4019-4024, 2014 | 136 | 2014 |
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation RS Singleton, P Liu-Yi, F Formenti, W Ge, R Sekirnik, R Fischer, J Adam, ... Proceedings of the National Academy of Sciences 111 (11), 4031-4036, 2014 | 134 | 2014 |
Oxygenase catalyzed 5-methylcytosine hydroxylation C Loenarz, CJ Schofield Chemistry & biology 16 (6), 580-583, 2009 | 118 | 2009 |
Kinetic rationale for selectivity toward N-and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases E Flashman, EAL Bagg, R Chowdhury, J Mecinovic, C Loenarz, ... Journal of Biological Chemistry 283 (7), 3808-3815, 2008 | 96 | 2008 |
A mechanism for induction of a hypoxic response by vaccinia virus M Mazzon, NE Peters, C Loenarz, EM Krysztofinska, SWJ Ember, ... Proceedings of the National Academy of Sciences 110 (30), 12444-12449, 2013 | 92 | 2013 |
Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2) E Davydova, AYY Ho, J Malecki, A Moen, JM Enserink, ME Jakobsson, ... Journal of Biological Chemistry 289 (44), 30499-30510, 2014 | 88 | 2014 |
Evidence for a stereoelectronic effect in human oxygen sensing C Loenarz, J Mecinović, R Chowdhury, LA McNeill, E Flashman, ... Angewandte Chemie International Edition 48 (10), 1784-1787, 2009 | 80 | 2009 |
Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2, 4-dicarboxylates A Thalhammer, J Mecinović, C Loenarz, A Tumber, NR Rose, ... Organic & biomolecular chemistry 9 (1), 127-135, 2011 | 77 | 2011 |
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth MJ Katz, JM Acevedo, C Loenarz, D Galagovsky, P Liu-Yi, M Pérez-Pepe, ... Proceedings of the National Academy of Sciences 111 (11), 4025-4030, 2014 | 53 | 2014 |