Joseph Minhow Chan, MD, PhD
Joseph Minhow Chan, MD, PhD
Thoracic Oncology Attending
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Analysis of the coding genome of diffuse large B-cell lymphoma
L Pasqualucci, V Trifonov, G Fabbri, J Ma, D Rossi, A Chiarenza, ...
Nature genetics 43 (9), 830-837, 2011
Transforming fusions of FGFR and TACC genes in human glioblastoma
D Singh, JM Chan, P Zoppoli, F Niola, R Sullivan, A Castano, EM Liu, ...
Science 337 (6099), 1231-1235, 2012
The integrated landscape of driver genomic alterations in glioblastoma
V Frattini, V Trifonov, JM Chan, A Castano, M Lia, F Abate, ST Keir, AX Ji, ...
Nature genetics 45 (10), 1141-1149, 2013
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution
O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ...
Cell 181 (2), 236-249, 2020
Topology of viral evolution
JM Chan, G Carlsson, R Rabadan
Proceedings of the National Academy of Sciences 110 (46), 18566-18571, 2013
Lineage plasticity in cancer: a shared pathway of therapeutic resistance
Á Quintanal-Villalonga, JM Chan, HA Yu, D Pe’er, CL Sawyers, T Sen, ...
Nature reviews Clinical oncology 17 (6), 360-371, 2020
Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype
V Grossmann, E Tiacci, AB Holmes, A Kohlmann, MP Martelli, W Kern, ...
Blood, The Journal of the American Society of Hematology 118 (23), 6153-6163, 2011
Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer
AJ Schoenfeld, JM Chan, D Kubota, H Sato, H Rizvi, Y Daneshbod, ...
Clinical Cancer Research 26 (11), 2654-2663, 2020
Concurrent RB1 and TP53 alterations define a subset of EGFR-mutant lung cancers at risk for histologic transformation and inferior clinical outcomes
M Offin, JM Chan, M Tenet, HA Rizvi, R Shen, GJ Riely, N Rekhtman, ...
Journal of Thoracic Oncology 14 (10), 1784-1793, 2019
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer
JM Chan, A Quintanal-Villalonga, VR Gao, Y Xie, V Allaj, O Chaudhary, ...
Cancer cell 39 (11), 1479-1496. e18, 2021
Emergence of fatal avian influenza in New England harbor seals
SJ Anthony, JA St. Leger, K Pugliares, HS Ip, JM Chan, ZW Carpenter, ...
MBio 3 (4), 10.1128/mbio. 00166-12, 2012
Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling
JM Chan, S Zaidi, JR Love, JL Zhao, M Setty, KM Wadosky, A Gopalan, ...
Science 377 (6611), 1180-1191, 2022
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity
A Chow, S Schad, MD Green, MD Hellmann, V Allaj, N Ceglia, G Zago, ...
Cancer Cell 39 (7), 973-988. e9, 2021
Multiomic analysis of lung tumors defines pathways activated in neuroendocrine transformation
A Quintanal-Villalonga, H Taniguchi, YA Zhan, MM Hasan, SS Chavan, ...
Cancer discovery 11 (12), 3028-3047, 2021
The miR-424 (322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland
D Llobet-Navas, R Rodríguez-Barrueco, V Castro, AP Ugalde, P Sumazin, ...
Genes & development 28 (7), 765-782, 2014
Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation
B Badal, A Solovyov, S Di Cecilia, JM Chan, LW Chang, R Iqbal, IT Aydin, ...
JCI insight 2 (9), 2017
Network analysis of global influenza spread
J Chan, A Holmes, R Rabadan
PLoS computational biology 6 (11), e1001005, 2010
WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
H Taniguchi, R Caeser, SS Chavan, YA Zhan, A Chow, P Manoj, F Uddin, ...
Cell reports 39 (7), 2022
Targeting lysine-specific demethylase 1 rescues major histocompatibility complex class I antigen presentation and overcomes programmed death-ligand 1 blockade resistance in SCLC
EM Nguyen, H Taniguchi, JM Chan, YA Zhan, X Chen, J Qiu, ...
Journal of Thoracic Oncology 17 (8), 1014-1031, 2022
The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer
A Chow, FZ Uddin, M Liu, A Dobrin, BY Nabet, L Mangarin, Y Lavin, ...
Immunity 56 (1), 93-106. e6, 2023
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