| kinITC: a new method for obtaining joint thermodynamic and kinetic data by isothermal titration calorimetry D Burnouf, E Ennifar, S Guedich, B Puffer, G Hoffmann, G Bec, F Disdier, ... Journal of the American Chemical Society 134 (1), 559-565, 2012 | 206 | 2012 |
| Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity S Gehrig, ME Eberle, F Botschen, K Rimbach, F Eberle, T Eigenbrod, ... Journal of Experimental Medicine 209 (2), 225-233, 2012 | 144 | 2012 |
| Reconstitution in vitro of the valyl-tRNA synthetase-elongation factor (EF) 1 beta gamma delta complex. Essential roles of the NH2-terminal extension of valyl-tRNA synthetase … G Bec, P Kerjan, JP Waller Journal of Biological Chemistry 269 (3), 2086-2092, 1994 | 126 | 1994 |
| The crystal structure of HIV reverse-transcription primer tRNA (Lys, 3) shows a canonical anticodon loop P Benas, G Bec, G Keith, R Marquet, C Ehresmann, B Ehresmann, ... Rna 6 (10), 1347-1355, 2000 | 122 | 2000 |
| Valyl-tRNA synthetase from rabbit liver: I. Purification as a heterotypic complex in association with elongation factor G Bec, P Kerjan, XD Zha, JP Waller Journal of Biological Chemistry 264 (35), 21131-21137, 1989 | 117 | 1989 |
| HIV-1 Vif binds to APOBEC3G mRNA and inhibits its translation G Mercenne, S Bernacchi, D Richer, G Bec, S Henriet, JC Paillart, ... Nucleic acids research 38 (2), 633-646, 2010 | 108 | 2010 |
| Extending ITC to Kinetics with kinITC P Dumas, E Ennifar, C Da Veiga, G Bec, W Palau, C Di Primo, A Piñeiro, ... Methods in enzymology 567, 157-180, 2016 | 85 | 2016 |
| Vif is a RNA chaperone that could temporally regulate RNA dimerization and the early steps of HIV-1 reverse transcription S Henriet, L Sinck, G Bec, RJ Gorelick, R Marquet, JC Paillart Nucleic acids research 35 (15), 5141-5153, 2007 | 84 | 2007 |
| Thermodynamics of HIV-1 reverse transcriptase in action elucidates the mechanism of action of non-nucleoside inhibitors G Bec, B Meyer, MA Gerard, J Steger, K Fauster, P Wolff, D Burnouf, ... Journal of the American Chemical Society 135 (26), 9743-9752, 2013 | 65 | 2013 |
| Discovery of Chiral Cyclopropyl Dihydro-Alkylthio-Benzyl-Oxopyrimidine (S-DABO) Derivatives as Potent HIV-1 Reverse Transcriptase Inhibitors with High Activity … M Radi, G Maga, M Alongi, L Angeli, A Samuele, S Zanoli, L Bellucci, ... Journal of medicinal chemistry 52 (3), 840-851, 2009 | 51 | 2009 |
| Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes S Werner, L Schmidt, V Marchand, T Kemmer, C Falschlunger, ... Nucleic acids research 48 (7), 3734-3746, 2020 | 50 | 2020 |
| In vitro evidence for the interaction of tRNA3Lys with U3 during the first strand transfer of HIV-1 reverse transcription F Brulé, G Bec, G Keith, SFJ Le Grice, BP Roques, B Ehresmann, ... Nucleic Acids Research 28 (2), 634-640, 2000 | 50 | 2000 |
| Transfer RNA recognition by the Escherichia coli delta2-isopentenyl-pyrophosphate: tRNA delta2-isopentenyl transferase: dependence on the anticodon arm structure. Y Motorin, G Bec, R Tewari, H Grosjean RNA 3 (7), 721-733, 1997 | 50 | 1997 |
| Quantitative and predictive model of kinetic regulation by E. coli TPP riboswitches S Guedich, B Puffer-Enders, M Baltzinger, G Hoffmann, C Da Veiga, ... RNA biology 13 (4), 373-390, 2016 | 48 | 2016 |
| Valyl-tRNA synthetase from rabbit liver: II. The enzyme derived from the high-Mr complex displays hydrophobic as well as polyanion-binding properties G Bec, JP Waller Journal of Biological Chemistry 264 (35), 21138-21143, 1989 | 48 | 1989 |
| Multiple phosphorylation sites and quaternary organization of guanine-nucleotide exchange complex of elongation factor-1 (EF-1βγδ/ValRS) control the various functions of EF-1α O Minella, O Mulner-Lorillon, G Bec, P Cormier, R Belle Bioscience reports 18, 119-127, 1998 | 42 | 1998 |
| Multianalytical study of the binding between a small chiral molecule and a DNA aptamer: evidence for asymmetric steric effect upon 3′-versus 5′-end sequence modification L Challier, R Miranda-Castro, B Barbe, C Fave, B Limoges, E Peyrin, ... Analytical chemistry 88 (23), 11963-11971, 2016 | 39 | 2016 |
| Crystal structure of HIV-1 reverse transcriptase bound to a non-nucleoside inhibitor with a novel mechanism of action S Freisz, G Bec, M Radi, P Wolff, E Crespan, L Angeli, P Dumas, G Maga, ... Angew Chem Int Ed Engl 49 (10), 1805-1808, 2010 | 38 | 2010 |
| Double methylation of tRNA-U54 to 2′-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7 P Keller, I Freund, V Marchand, G Bec, R Huang, Y Motorin, T Eigenbrod, ... Nucleic acids research 46 (18), 9764-9775, 2018 | 24 | 2018 |
| Effects of tRNA3Lys aminoacylation on the initiation of HIV-1 reverse transcription M Rigourd, G Bec, P Bénas, SFJ Le Grice, B Ehresmann, C Ehresmann, ... Biochimie 85 (5), 521-525, 2003 | 19 | 2003 |
