David G. Harrison
David G. Harrison
Professor of Medicine, Vanderbilt University
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Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress
H Cai, DG Harrison
Circulation research 87 (10), 840-844, 2000
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.
S Rajagopalan, S Kurz, T Münzel, M Tarpey, BA Freeman, KK Griendling, ...
The Journal of clinical investigation 97 (8), 1916-1923, 1996
Hypercholesterolemia increases endothelial superoxide anion production.
Y Ohara, TE Peterson, DG Harrison
The Journal of clinical investigation 91 (6), 2546-2551, 1993
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
U Landmesser, S Dikalov, SR Price, L McCann, T Fukai, SM Holland, ...
The Journal of clinical investigation 111 (8), 1201-1209, 2003
Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction
TJ Guzik, NE Hoch, KA Brown, LA McCann, A Rahman, S Dikalov, ...
The Journal of experimental medicine 204 (10), 2449-2460, 2007
Role of oxidative stress in atherosclerosis
D Harrison, KK Griendling, U Landmesser, B Hornig, H Drexler
The American journal of cardiology 91 (3), 7-11, 2003
Does visual interpretation of the coronary arteriogram predict the physiologic importance of a coronary stenosis?
CW White, CB Wright, DB Doty, LF Hiratza, CL Eastham, DG Harrison, ...
New England Journal of Medicine 310 (13), 819-824, 1984
Mechanisms underlying endothelial dysfunction in diabetes mellitus
U Hink, H Li, H Mollnau, M Oelze, E Matheis, M Hartmann, M Skatchkov, ...
Circulation research 88 (2), e14-e22, 2001
Cellular and molecular mechanisms of endothelial cell dysfunction.
DG Harrison
The Journal of clinical investigation 100 (9), 2153-2157, 1997
Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque …
S Rajagopalan, XP Meng, S Ramasamy, DG Harrison, ZS Galis
The Journal of clinical investigation 98 (11), 2572-2579, 1996
Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide
PR Myers, RL Minor, R Guerra, JN Bates, DG Harrison
Nature 345, 161-163, 1990
Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure
G Kojda, D Harrison
Cardiovascular research 43 (3), 652-671, 1999
Role of superoxide in angiotensin II–induced but not catecholamine-induced hypertension
JB Laursen, S Rajagopalan, Z Galis, M Tarpey, BA Freeman, DG Harrison
Circulation 95 (3), 588-593, 1997
Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase.
K Nishida, DG Harrison, JP Navas, AA Fisher, SP Dockery, M Uematsu, ...
The Journal of clinical investigation 90 (5), 2092-2096, 1992
Increased NADH-oxidase–mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system
A Warnholtz, G Nickenig, E Schulz, R Macharzina, JH Bräsen, ...
Circulation 99 (15), 2027-2033, 1999
Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin
JB Laursen, M Somers, S Kurz, L McCann, A Warnholtz, BA Freeman, ...
Circulation 103 (9), 1282-1288, 2001
Inflammation, immunity, and hypertension
DG Harrison, TJ Guzik, HE Lob, MS Madhur, PJ Marvar, SR Thabet, ...
Hypertension 57 (2), 132-140, 2011
The vascular NAD (P) H oxidases as therapeutic targets in cardiovascular diseases
H Cai, KK Griendling, DG Harrison
Trends in pharmacological sciences 24 (9), 471-478, 2003
Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase
N Kuzkaya, N Weissmann, DG Harrison, S Dikalov
Journal of Biological Chemistry 278 (25), 22546-22554, 2003
Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance.
T Münzel, H Sayegh, BA Freeman, MM Tarpey, DG Harrison
The Journal of clinical investigation 95 (1), 187-194, 1995
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