| Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3681 | 2017 |
| The GTEx Consortium atlas of genetic regulatory effects across human tissues GTEx Consortium Science 369 (6509), 1318-1330, 2020 | 3508 | 2020 |
| A quantitative proteome map of the human body L Jiang, M Wang, S Lin, R Jian, X Li, J Chan, G Dong, H Fang, ... Cell 183 (1), 269-283. e19, 2020 | 392 | 2020 |
| Regulatory genomic circuitry of human disease loci by integrative epigenomics CA Boix, BT James, YP Park, W Meuleman, M Kellis Nature 590 (7845), 300-307, 2021 | 338 | 2021 |
| Deep learning for regulatory genomics Y Park, M Kellis Nature biotechnology 33 (8), 825-826, 2015 | 221 | 2015 |
| Co-expression networks reveal the tissue-specific regulation of transcription and splicing A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ... Genome research 27 (11), 1843-1858, 2017 | 186 | 2017 |
| Human microglial state dynamics in Alzheimer’s disease progression N Sun, MB Victor, YP Park, X Xiong, AN Scannail, N Leary, S Prosper, ... Cell 186 (20), 4386-4403. e29, 2023 | 182 | 2023 |
| Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease Nature genetics 49 (12), 1664-1670, 2017 | 151 | 2017 |
| Genetic drivers of m6A methylation in human brain, lung, heart and muscle X Xiong, L Hou, YP Park, B Molinie, ... Nature genetics 53 (8), 1156-1165, 2021 | 103 | 2021 |
| Epigenomic dissection of Alzheimer’s disease pinpoints causal variants and reveals epigenome erosion X Xiong, BT James, CA Boix, YP Park, K Galani, MB Victor, N Sun, L Hou, ... Cell 186 (20), 4422-4437. e21, 2023 | 94 | 2023 |
| Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease N Sun, LA Akay, MH Murdock, Y Park, F Galiana-Melendez, A Bubnys, ... Nature neuroscience 26 (6), 970-982, 2023 | 82 | 2023 |
| Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis F Yang, J Wang, BL Pierce, LS Chen, F Aguet, KG Ardlie, BB Cummings, ... Genome research 27 (11), 1859-1871, 2017 | 71 | 2017 |
| Analysis of genetically regulated gene expression identifies a prefrontal PTSD gene, SNRNP35, specific to military cohorts LM Huckins, C Chatzinakos, MS Breen, J Hartmann, T Klengel, ... Cell reports 31 (9), 2020 | 68 | 2020 |
| The housekeeping gene hypoxanthine guanine phosphoribosyltransferase (HPRT) regulates multiple developmental and metabolic pathways of murine embryonic stem cell neuronal … TH Kang, Y Park, JS Bader, T Friedmann PloS one 8 (10), e74967, 2013 | 63 | 2013 |
| Genes with high network connectivity are enriched for disease heritability SS Kim, C Dai, F Hormozdiari, B van de Geijn, S Gazal, Y Park, ... The American Journal of Human Genetics 104 (5), 896-913, 2019 | 62 | 2019 |
| Dynamic networks from hierarchical bayesian graph clustering Y Park, C Moore, JS Bader PloS one 5 (1), e8118, 2010 | 48 | 2010 |
| How networks change with time Y Park, JS Bader Bioinformatics 28 (12), i40-i48, 2012 | 47 | 2012 |
| Network-based inference of cancer progression from microarray data Y Park, S Shackney, R Schwartz IEEE/ACM Transactions on Computational Biology and Bioinformatics 6 (2), 200-212, 2008 | 37 | 2008 |
| Resolving the structure of interactomes with hierarchical agglomerative clustering Y Park, JS Bader BMC bioinformatics 12, 1-10, 2011 | 31 | 2011 |
| Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer’s disease L He, Y Loika, Y Park, Genotype Tissue Expression (GTEx) consortium, ... Translational psychiatry 11 (1), 146, 2021 | 27 | 2021 |
Manolis KellisProfessor of Computer Science, MIT and Broad InstituteVerified email at mit.edu
