| Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins JA Frost, H Steen, P Shapiro, T Lewis, N Ahn, PE Shaw, MH Cobb The EMBO journal 16 (21), 6426-6438, 1997 | 536 | 1997 |
| Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity A Lin, J Frost, T Deng, T Smeal, N Al-Alawi, U Kikkawa, T Hunter, ... Cell 70 (5), 777-789, 1992 | 470 | 1992 |
| Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members JA Frost, S Xu, MR Hutchison, S Marcus, MH Cobb Molecular and cellular biology 16 (7), 3707-3713, 1996 | 358 | 1996 |
| Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338 A Chaudhary, WG King, MD Mattaliano, JA Frost, B Diaz, DK Morrison, ... Current Biology 10 (9), 551-554, 2000 | 309 | 2000 |
| A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum. JA Frost, TD Geppert, MH Cobb, JR Feramisco Proceedings of the National Academy of Sciences 91 (9), 3844-3848, 1994 | 271 | 1994 |
| Differential effects of PAK1-activating mutations reveal activity-dependent and-independent effects on cytoskeletal regulation JA Frost, A Khokhlatchev, S Stippec, MA White, MH Cobb Journal of Biological Chemistry 273 (43), 28191-28198, 1998 | 246 | 1998 |
| Stimulation of NFκB activity by multiple signaling pathways requires PAK1 JA Frost, JL Swantek, S Stippec, MJ Yin, R Gaynor, MH Cobb Journal of Biological Chemistry 275 (26), 19693-19699, 2000 | 245 | 2000 |
| Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy. J Thorburn, JA Frost, A Thorburn The Journal of cell biology 126 (6), 1565-1572, 1994 | 229 | 1994 |
| MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase. S Xu, D Robbins, J Frost, A Dang, C Lange-Carter, MH Cobb Proceedings of the National Academy of Sciences 92 (15), 6808-6812, 1995 | 213 | 1995 |
| Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells CS Pichot, SM Hartig, L Xia, C Arvanitis, D Monisvais, FY Lee, JA Frost, ... British journal of cancer 101 (1), 38-47, 2009 | 197 | 2009 |
| B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms NH Tran, X Wu, JA Frost Journal of Biological Chemistry 280 (16), 16244-16253, 2005 | 197 | 2005 |
| Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition NH Tran, JA Frost Journal of Biological Chemistry 278 (13), 11221-11226, 2003 | 153 | 2003 |
| p21-activated kinase 1 plays a critical role in cellular activation by Nef OT Fackler, X Lu, JA Frost, M Geyer, B Jiang, W Luo, A Abo, AS Alberts, ... Molecular and cellular biology 20 (7), 2619-2627, 2000 | 144 | 2000 |
| Persistent pain after spinal cord injury is maintained by primary afferent activity Q Yang, Z Wu, JK Hadden, MA Odem, Y Zuo, RJ Crook, JA Frost, ... Journal of Neuroscience 34 (32), 10765-10769, 2014 | 141 | 2014 |
| Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp CS Pichot, C Arvanitis, SM Hartig, SA Jensen, J Bechill, S Marzouk, J Yu, ... Cancer research 70 (21), 8347-8356, 2010 | 141 | 2010 |
| Activation of Mitogen-activated Protein Kinase Cascades by p21-activated Protein Kinases in Cell-free Extracts of Xenopus Oocytes (∗) A Polverino, J Frost, P Yang, M Hutchison, AM Neiman, MH Cobb, ... Journal of Biological Chemistry 270 (44), 26067-26070, 1995 | 123 | 1995 |
| Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity JA Frost, AS Alberts, E Sontag, K Guan, MC Mumby, JR Feramisco Molecular and cellular biology 14 (9), 6244-6252, 1994 | 122 | 1994 |
| PAK1 negatively regulates the activity of the Rho exchange factor NET1 AS Alberts, H Qin, HS Carr, JA Frost Journal of Biological Chemistry 280 (13), 12152-12161, 2005 | 99 | 2005 |
| c-Myc Cooperates with Activated Ras To Induce the cdc2 Promoter TL Born, JA Frost, A Schönthal, GC Prendergast, JR Feramisco Molecular and cellular biology 14 (9), 5710-5718, 1994 | 94 | 1994 |
| The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells A Dang, JA Frost, MH Cobb Journal of Biological Chemistry 273 (31), 19909-19913, 1998 | 89 | 1998 |
