Irena Levitan
Irena Levitan
Professor of Medicine
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Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies
R Zidovetzki, I Levitan
Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (6), 1311-1324, 2007
Oxidized LDL: diversity, patterns of recognition, and pathophysiology
I Levitan, S Volkov, PV Subbaiah
Antioxidants & redox signaling 13 (1), 39-75, 2010
Cholesterol depletion increases membrane stiffness of aortic endothelial cells
FJ Byfield, H Aranda-Espinoza, VG Romanenko, GH Rothblat, I Levitan
Biophysical journal 87 (5), 3336-3343, 2004
Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D
FJ Byfield, RK Reen, TP Shentu, I Levitan, KJ Gooch
Journal of biomechanics 42 (8), 1114-1119, 2009
Expression of nuclear genes as affected by treatments acting on the plastids
R Oelmüller, I Levitan, R Bergfeld, VK Rajasekhar, H Mohr
Planta 168 (4), 482-492, 1986
Cholesterol and ion channels
I Levitan, Y Fang, A Rosenhouse-Dantsker, V Romanenko
Cholesterol binding and cholesterol transport proteins: structure and …, 2010
New mechanisms of pulmonary arterial hypertension: role of Ca2+ signaling
FK Kuhr, KA Smith, MY Song, I Levitan, JXJ Yuan
American journal of physiology-heart and circulatory physiology 302 (8 …, 2012
Membrane cholesterol content modulates activation of volume-regulated anion current in bovine endothelial cells
I Levitan, AE Christian, TN Tulenko, GH Rothblat
The Journal of general physiology 115 (4), 405-416, 2000
Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol
SL Liu, R Sheng, JH Jung, L Wang, E Stec, MJ O'Connor, S Song, ...
Nature chemical biology 13 (3), 268-274, 2017
Cholesterol binding to ion channels
I Levitan, DK Singh, A Rosenhouse-Dantsker
Frontiers in physiology 5, 78002, 2014
The effect of cellular cholesterol on membrane-cytoskeleton adhesion
M Sun, N Northup, F Marga, T Huber, FJ Byfield, I Levitan, G Forgacs
Journal of cell science 120 (13), 2223-2231, 2007
Modulation of endothelial inward-rectifier K+ current by optical isomers of cholesterol
VG Romanenko, GH Rothblat, I Levitan
Biophysical journal 83 (6), 3211-3222, 2002
Cholesterol sensitivity and lipid raft targeting of Kir2. 1 channels
VG Romanenko, Y Fang, F Byfield, AJ Travis, CA Vandenberg, ...
Biophysical journal 87 (6), 3850-3861, 2004
Hypercholesterolemia Suppresses Inwardly Rectifying K+ Channels in Aortic Endothelium In Vitro and In Vivo
Y Fang, ER Mohler III, E Hsieh, H Osman, SM Hashemi, PF Davies, ...
Circulation research 98 (8), 1064-1071, 2006
OxLDL increases endothelial stiffness, force generation, and network formation
FJ Byfield, S Tikku, GH Rothblat, KJ Gooch, I Levitan
Journal of lipid research 47 (4), 715-723, 2006
Identification of novel cholesterol-binding regions in Kir2 channels
A Rosenhouse-Dantsker, S Noskov, S Durdagi, DE Logothetis, I Levitan
Journal of Biological Chemistry 288 (43), 31154-31164, 2013
Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells
S Chatterjee, AB Al-Mehdi, I Levitan, T Stevens, AB Fisher
American Journal of Physiology-Cell Physiology 285 (4), C959-C967, 2003
Modulation of a volume-regulated chloride current by F-actin
I Levitan, C Almonte, P Mollard, SS Garber
The Journal of membrane biology 147, 283-294, 1995
Identification of a C-terminus domain critical for the sensitivity of Kir2. 1 to cholesterol
Y Epshtein, AP Chopra, A Rosenhouse-Dantsker, GB Kowalsky, ...
Proceedings of the National Academy of Sciences 106 (19), 8055-8060, 2009
Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells
J Oshikawa, SJ Kim, E Furuta, C Caliceti, GF Chen, RD McKinney, F Kuhr, ...
American Journal of Physiology-Heart and Circulatory Physiology 302 (3 …, 2012
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