| Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection W Li, C Chen, A Drelich, DR Martinez, LE Gralinski, Z Sun, A Schäfer, ... Proceedings of the National Academy of Sciences 117 (47), 29832-29838, 2020 | 88 | 2020 |
| Enhancement of the tumor penetration of monoclonal antibody by fusion of a neuropilin-targeting peptide improves the antitumor efficacy TH Shin, ES Sung, YJ Kim, KS Kim, SH Kim, SK Kim, YD Lee, YS Kim Molecular cancer therapeutics 13 (3), 651-661, 2014 | 66 | 2014 |
| A heterodimeric Fc-based bispecific antibody simultaneously targeting VEGFR-2 and Met exhibits potent antitumor activity HJ Choi, YJ Kim, S Lee, YS Kim Molecular cancer therapeutics 12 (12), 2748-2759, 2013 | 61 | 2013 |
| Co-targeting of EGF receptor and neuropilin-1 overcomes cetuximab resistance in pancreatic ductal adenocarcinoma with integrin β1-driven Src-Akt bypass signaling YJ Kim, K Jung, DS Baek, SS Hong, YS Kim Oncogene 36 (18), 2543-2552, 2017 | 53 | 2017 |
| Copper chaperone ATOX1 is required for MAPK signaling and growth in BRAF mutation-positive melanoma YJ Kim, GJ Bond, T Tsang, JM Posimo, L Busino, DC Brady Metallomics 11 (8), 1430-1440, 2019 | 41 | 2019 |
| A neuropilin-1 antagonist exerts antitumor immunity by inhibiting the suppressive function of intratumoral regulatory T cells K Jung, JA Kim, YJ Kim, HW Lee, CH Kim, S Haam, YS Kim Cancer Immunology Research 8 (1), 46-56, 2020 | 38 | 2020 |
| Immunoglobulin Fc-fused, neuropilin-1-specific peptide shows efficient tumor tissue penetration and inhibits tumor growth via anti-angiogenesis YJ Kim, J Bae, TH Shin, SH Kang, M Jeong, Y Han, JH Park, SK Kim, ... Journal of controlled release 216, 56-68, 2015 | 35 | 2015 |
| Inhibition of BCL2 Family Members Increases the Efficacy of Copper Chelation in BRAFV600E-Driven Melanoma YJ Kim, T Tsang, GR Anderson, JM Posimo, DC Brady Cancer research 80 (7), 1387-1400, 2020 | 32 | 2020 |
| Engineering of immunoglobulin Fc heterodimers using yeast surface-displayed combinatorial Fc library screening HJ Choi, YJ Kim, DK Choi, YS Kim PloS one 10 (12), e0145349, 2015 | 30 | 2015 |
| Heterodimeric Fc-fused IL12 shows potent antitumor activity by generating memory CD8+ T cells K Jung, JH Ha, JE Kim, JA Kim, YJ Kim, CH Kim, YS Kim Oncoimmunology 7 (7), e1438800, 2018 | 29 | 2018 |
| Dual-targeting of EGFR and Neuropilin-1 attenuates resistance to EGFR-targeted antibody therapy in KRAS-mutant non-small cell lung cancer YJ Kim, DS Baek, S Lee, D Park, HN Kang, BC Cho, YS Kim Cancer letters 466, 23-34, 2019 | 28 | 2019 |
| The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation M Grasso, GJ Bond, YJ Kim, S Boyd, MM Dzebo, S Valenzuela, T Tsang, ... Journal of Biological Chemistry 297 (6), 2021 | 23 | 2021 |
| Crystal structures of immunoglobulin Fc heterodimers reveal the molecular basis for heterodimer formation HJ Choi, SH Seok, YJ Kim, MD Seo, YS Kim Molecular Immunology 65 (2), 377-383, 2015 | 22 | 2015 |
| A highly-specific fully-human antibody and CAR-T cells targeting CD66e/CEACAM5 are cytotoxic for CD66e-expressing cancer cells in vitro and in vivo DS Baek, YJ Kim, S Vergara, A Conard, C Adams, G Calero, R Ishima, ... Cancer letters 525, 97-107, 2022 | 14 | 2022 |
| Immunoglobulin Fc-fused peptide without C-terminal Arg or Lys residue augments neuropilin-1-dependent tumor vascular permeability DS Baek, JH Kim, YJ Kim, YS Kim Molecular pharmaceutics 15 (2), 394-402, 2018 | 9 | 2018 |
| Heterodimeric Fc-fused cytokine and pharmaceutical composition comprising the same YS Kim, K Jung, JH Ha, DK Choi, HJ Choi, YJ Kim US Patent 10,696,722, 2020 | 7 | 2020 |
| Chimeric antigen receptor-T cells are effective against CEACAM5 expressing non-small cell lung cancer cells resistant to antibody-drug conjugates YJ Kim, W Li, DV Zhelev, JW Mellors, DS Dimitrov, DS Baek Frontiers in Oncology 13, 1124039, 2023 | 6 | 2023 |
| Heterodimeric Fc-fused cytokine and pharmaceutical composition comprising the same YS Kim, K Jung, JH Ha, DK Choi, HJ Choi, YJ Kim US Patent 11,078,249, 2021 | 2 | 2021 |
| IL-21 (heterodimeric Fc-fused IL-21) fused to immunoglobulin heavy chain constant region heterodimer (heterodimeric Fc), and pharmaceutical composition comprising same KM Lee, SA Lim, YS Kim, YJ Kim US Patent 10,800,825, 2020 | 2 | 2020 |
| Structural and molecular determinants of CCS-mediated copper activation of MEK1/2 M Grasso, GJ Bond, YJ Kim, KB Alwan, S Boyd, MM Dzebo, S Valenzuela, ... bioRxiv, 2020.05. 01.072124, 2020 | 2 | 2020 |
