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David Mowrey
David Mowrey
Senior Research Scientist, Icagen-T
Verified email at icagen.com
Title
Cited by
Cited by
Year
Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine
J Pan, Q Chen, D Willenbring, D Mowrey, XP Kong, A Cohen, CB Divito, ...
Structure 20 (9), 1463-1469, 2012
942012
p62-dependent phase separation of patient-derived KEAP1 mutations and NRF2
EW Cloer, PF Siesser, EM Cousins, D Goldfarb, DD Mowrey, JS Harrison, ...
Molecular and cellular biology, 2018
642018
NMR structures of the human α7 nAChR transmembrane domain and associated anesthetic binding sites
V Bondarenko, DD Mowrey, TS Tillman, E Seyoum, Y Xu, P Tang
Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (5), 1389-1395, 2014
632014
Asymmetric ligand binding facilitates conformational transitions in pentameric ligand-gated ion channels
D Mowrey, MH Cheng, LT Liu, D Willenbring, X Lu, T Wymore, Y Xu, ...
Journal of the American Chemical Society 135 (6), 2172-2180, 2013
522013
Insights into distinct modulation of α7 and α7β2 nicotinic acetylcholine receptors by the volatile anesthetic isoflurane
DD Mowrey, Q Liu, V Bondarenko, Q Chen, E Seyoum, Y Xu, J Wu, ...
Journal of Biological Chemistry 288 (50), 35793-35800, 2013
492013
Conformational changes underlying desensitization of the pentameric ligand-gated ion channel ELIC
MN Kinde, Q Chen, MJ Lawless, DD Mowrey, J Xu, S Saxena, Y Xu, ...
Structure 23 (6), 995-1004, 2015
482015
Open-channel structures of the human glycine receptor α1 full-length transmembrane domain
DD Mowrey, T Cui, Y Jia, D Ma, AM Makhov, P Zhang, P Tang, Y Xu
Structure 21 (10), 1897-1904, 2013
482013
Isoflurane Alters the Structure and Dynamics of GLIC
D Willenbring, LT Liu, D Mowrey, Y Xu, P Tang
Biophysical Journal 101 (8), 1905-1912, 2011
472011
Percolation model of sensory transmission and loss of consciousness under general anesthesia
DW Zhou, DD Mowrey, P Tang, Y Xu
Physical review letters 115 (10), 108103, 2015
452015
NMR structures of the transmembrane domains of the α4β2 nAChR
V Bondarenko, D Mowrey, T Tillman, T Cui, LT Liu, Y Xu, P Tang
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (5), 1261-1268, 2012
432012
NMR Structure and Dynamics of Water-Solubilized Transmembrane Domains of Nicotinic Acetylcholine Receptor
T Cui, D Mowrey, V Bondarenko, T Tillman, D Ma, E Landrum, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes, 2011
39*2011
β-Methylamino-L-alanine substitution of serine in SOD1 suggests a direct role in ALS etiology
EA Proctor, DD Mowrey, NV Dokholyan
PLoS computational biology 15 (7), e1007225, 2019
322019
NMR resolved multiple anesthetic binding sites in the TM domains of the α4β2 nAChR
V Bondarenko, D Mowrey, LT Liu, Y Xu, P Tang
Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (2), 398-404, 2013
322013
Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor α1 for the treatment of pain
MM Wells, TS Tillman, DD Mowrey, T Sun, Y Xu, P Tang
Journal of medicinal chemistry 58 (7), 2958-2966, 2015
312015
Signal transduction pathways in the pentameric ligand-gated ion channels
D Mowrey, Q Chen, Y Liang, J Liang, Y Xu, P Tang
PLoS One 8 (5), e64326, 2013
292013
ELIC-α7 Nicotinic acetylcholine receptor (α7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation
TS Tillman, E Seyoum, DD Mowrey, Y Xu, P Tang
Journal of Biological Chemistry 289 (20), 13851-13857, 2014
282014
Tyrosine phosphorylation switching of a G protein
B Li, M Tunc-Ozdemir, D Urano, H Jia, EG Werth, DD Mowrey, LM Hicks, ...
Journal of Biological Chemistry 293 (13), 4752-4766, 2018
252018
Unresponsive Correlated Motion in α7 nAChR to Halothane Binding Explains Its Functional Insensitivity to Volatile Anesthetics
D Mowrey, EJ Haddadian, LT Liu, D Willenbring, Y Xu, P Tang
The Journal of Physical Chemistry B 114 (22), 7649-7655, 2010
232010
Channel gating dependence on pore lining helix glycine residues in skeletal muscle ryanodine receptor
Y Mei, L Xu, DD Mowrey, RM Giraldez, Y Wang, DA Pasek, NV Dokholyan, ...
Journal of Biological Chemistry 290 (28), 17535-17545, 2015
192015
Syntheses of ketamine and related analogues: A mini review
I Dimitrov, WA Denny, J Jose
Synthesis 50 (21), 4201-4215, 2018
152018
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