Thomas Southworth
Thomas Southworth
The University of Manchester
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α, β-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases
N Moretto, F Facchinetti, T Southworth, M Civelli, D Singh, R Patacchini
American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (5 …, 2009
The ExsA Protein of Bacillus cereus Is Required for Assembly of Coat and Exosporium onto the Spore Surface
K Bailey-Smith, SJ Todd, TW Southworth, J Proctor, A Moir
Journal of bacteriology 187 (11), 3800-3806, 2005
GerN, an Endospore Germination Protein ofBacillus cereus, Is an Na+/H+-K+ Antiporter
TW Southworth, AA Guffanti, A Moir, TA Krulwich
Journal of Bacteriology 183 (20), 5896-5903, 2001
Novel ligands for the extracellular solute receptors of two bacterial TRAP transporters
GH Thomas, T Southworth, MR Leon-Kempis, A Leech, DJ Kelly
Microbiology 152 (1), 187-198, 2006
IFN‐γ synergistically enhances LPS signalling in alveolar macrophages from COPD patients and controls by corticosteroid‐resistant STAT1 activation
T Southworth, A Metryka, S Lea, S Farrow, J Plumb, D Singh
British journal of pharmacology 166 (7), 2070-2083, 2012
Pulmonary inflammation in patients with chronic obstructive pulmonary disease with higher blood eosinophil counts
U Kolsum, G Damera, TH Pham, T Southworth, S Mason, P Karur, ...
Journal of Allergy and Clinical Immunology 140 (4), 1181-1184. e7, 2017
GerN, an Antiporter Homologue Important in Germination of Bacillus cereus Endospores
PD Thackray, J Behravan, TW Southworth, A Moir
Journal of bacteriology 183 (2), 476-482, 2001
CRTH2 antagonists in asthma: current perspectives
D Singh, A Ravi, T Southworth
Clinical pharmacology: advances and applications 9, 165, 2017
The reproducibility of COPD blood eosinophil counts
T Southworth, G Beech, P Foden, U Kolsum, D Singh
European Respiratory Journal 52 (1), 2018
The effects of corticosteroids on COPD lung macrophages: a pooled analysis
A Higham, G Booth, S Lea, T Southworth, J Plumb, D Singh
Respiratory research 16 (1), 1-9, 2015
Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients
T Southworth, J Plumb, V Gupta, J Pearson, I Ramis, MD Lehner, ...
Respiratory research 17 (1), 1-12, 2016
Clinical characteristics of eosinophilic COPD versus COPD patients with a history of asthma
U Kolsum, A Ravi, P Hitchen, S Maddi, T Southworth, D Singh
Respiratory research 18 (1), 1-7, 2017
Characterization of the inflammatory response to inhaled lipopolysaccharide in mild to moderate chronic obstructive pulmonary disease
V Gupta, A Banyard, A Mullan, S Sriskantharajah, T Southworth, D Singh
British journal of clinical pharmacology 79 (5), 767-776, 2015
Mutational Loss of a K+ and NH4+ Transporter Affects the Growth and Endospore Formation of Alkaliphilic Bacillus pseudofirmus OF4
Y Wei, TW Southworth, H Kloster, M Ito, AA Guffanti, A Moir, TA Krulwich
Journal of bacteriology 185 (17), 5133-5147, 2003
The effect of phosphatidylinositol-3 kinase inhibition on matrix metalloproteinase-9 and reactive oxygen species release from chronic obstructive pulmonary disease neutrophils
V Gupta, A Khan, A Higham, J Lemon, S Sriskantharajah, A Amour, ...
International immunopharmacology 35, 155-162, 2016
The effects of smoking on the lipopolysaccharide response and glucocorticoid sensitivity of alveolar macrophages of patients with asthma
B Kane, U Kolsum, T Southworth, J Armstrong, A Woodcock, D Singh
Chest 136 (1), 163-170, 2009
The stability of blood Eosinophils in chronic obstructive pulmonary disease
GH Long, T Southworth, U Kolsum, GC Donaldson, JA Wedzicha, ...
Respiratory research 21 (1), 1-4, 2020
Increased type 2 inflammation post rhinovirus infection in patients with moderate asthma
T Southworth, C Pattwell, N Khan, SF Mowbray, RM Strieter, ...
Cytokine 125, 154857, 2020
PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge
T Southworth, S Mason, A Bell, I Ramis, M Calbet, A Domenech, N Prats, ...
Biomarker research 6 (1), 1-8, 2018
Reduced exhaled breath condensate pH in asthmatic smokers using inhaled corticosteroids
B Kane, Z Borrill, T Southworth, A Woodcock, D Singh
Respirology 14 (3), 419-423, 2009
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