Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer ES Radisky, DC Radisky Journal of mammary gland biology and neoplasia 15, 201-212, 2010 | 639 | 2010 |
Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer C Mehner, A Hockla, E Miller, S Ran, DC Radisky, ES Radisky Oncotarget 5 (9), 2736, 2014 | 430 | 2014 |
Novel cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya DC Radisky, ES Radisky, LR Barrows, BR Copp, RA Kramer, CM Ireland Journal of the American Chemical Society 115 (5), 1632-1638, 1993 | 274 | 1993 |
MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits H Liu, DC Radisky, D Yang, R Xu, ES Radisky, MJ Bissell, JM Bishop Nature cell biology 14 (6), 567-574, 2012 | 207 | 2012 |
A clogged gutter mechanism for protease inhibitors ES Radisky, DE Koshland Jr Proceedings of the National Academy of Sciences 99 (16), 10316-10321, 2002 | 186 | 2002 |
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates ES Radisky, JM Lee, CJK Lu, DE Koshland Jr Proceedings of the National Academy of Sciences 103 (18), 6835-6840, 2006 | 180 | 2006 |
Matrix metalloproteinases as breast cancer drivers and therapeutic targets ES Radisky, DC Radisky Frontiers in bioscience (Landmark edition) 20, 1144, 2015 | 175 | 2015 |
Stromal induction of breast cancer: inflammation and invasion ES Radisky, DC Radisky Reviews in Endocrine and Metabolic Disorders 8, 279-287, 2007 | 171 | 2007 |
Haplotype analysis of hemochromatosis: evaluation of different linkage-disequilibrium approaches and evolution of disease chromosomes RS Ajioka, LB Jorde, JR Gruen, P Yu, D Dimitrova, J Barrow, E Radisky, ... The American Journal of Human Genetics 60 (6), 1439-1447, 1997 | 167 | 1997 |
Therapeutic potential of matrix metalloproteinase inhibition in breast cancer ES Radisky, M Raeeszadeh‐Sarmazdeh, DC Radisky Journal of cellular biochemistry 118 (11), 3531-3548, 2017 | 160 | 2017 |
Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2 J Batra, J Robinson, AS Soares, AP Fields, DC Radisky, ES Radisky Journal of Biological Chemistry 287 (19), 15935-15946, 2012 | 140 | 2012 |
Matrix metalloproteinase-10 is required for lung cancer stem cell maintenance, tumor initiation and metastatic potential V Justilien, RP Regala, IC Tseng, MP Walsh, J Batra, ES Radisky, ... PloS one 7 (4), e35040, 2012 | 129 | 2012 |
Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression ML Stallings-Mann, J Waldmann, Y Zhang, E Miller, ML Gauthier, ... Science translational medicine 4 (142), 142ra95-142ra95, 2012 | 123 | 2012 |
Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinoma C Mehner, E Miller, A Nassar, WR Bamlet, ES Radisky, DC Radisky Genes & cancer 6 (11-12), 480, 2015 | 116 | 2015 |
The iron-responsive element binding protein. Purification, cloning, and regulation in rat liver. Y Yu, E Radisky, EA Leibold Journal of Biological Chemistry 267 (26), 19005-19010, 1992 | 108 | 1992 |
FAM111A protects replication forks from protein obstacles via its trypsin-like domain Y Kojima, Y Machida, S Palani, TR Caulfield, ES Radisky, SH Kaufmann, ... Nature Communications 11 (1), 1318, 2020 | 94 | 2020 |
Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109 A Hockla, DC Radisky, ES Radisky Breast cancer research and treatment 124, 27-38, 2010 | 81 | 2010 |
Uroporphyrinogen decarboxylase: a splice site mutation causes the deletion of exon 6 in multiple families with porphyria cutanea tarda. JR Garey, LM Harrison, KF Franklin, KM Metcalf, ES Radisky, JP Kushner The Journal of clinical investigation 86 (5), 1416-1422, 1990 | 77 | 1990 |
Development of high affinity and high specificity inhibitors of matrix metalloproteinase 14 through computational design and directed evolution V Arkadash, G Yosef, J Shirian, I Cohen, Y Horev, M Grossman, I Sagi, ... Journal of Biological Chemistry 292 (8), 3481-3495, 2017 | 76 | 2017 |
Tumor cell–derived MMP3 Orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma C Mehner, E Miller, D Khauv, A Nassar, AL Oberg, WR Bamlet, L Zhang, ... Molecular Cancer Research 12 (10), 1430-1439, 2014 | 72 | 2014 |