Richard Oreffo
Richard Oreffo
Professor of Musculoskeletal Science
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Cited by
Cited by
The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder
MJ Dalby, N Gadegaard, R Tare, A Andar, MO Riehle, P Herzyk, ...
Nature materials 6 (12), 997-1003, 2007
Osteogenesis and angiogenesis: the potential for engineering bone
JM Kanczler, RO Oreffo
Eur Cell Mater 15 (2), 100-114, 2008
Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate
MJ Dalby, N Gadegaard, ROC Oreffo
Nature materials 13 (6), 558-569, 2014
Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo.
IR Garrett, BF Boyce, RO Oreffo, L Bonewald, J Poser, GR Mundy
The Journal of clinical investigation 85 (3), 632-639, 1990
Bone tissue engineering: hope vs hype
FRAJ Rose, ROC Oreffo
Biochemical and biophysical research communications 292 (1), 1-7, 2002
Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency
RJ McMurray, N Gadegaard, PM Tsimbouri, KV Burgess, LE McNamara, ...
Nature materials 10 (8), 637-644, 2011
Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration
D Tang, RS Tare, LY Yang, DF Williams, KL Ou, ROC Oreffo
Biomaterials 83, 363-382, 2016
Quality of life in sarcopenia and frailty
R Rizzoli, JY Reginster, JF Arnal, I Bautmans, C Beaudart, ...
Calcified tissue international 93, 101-120, 2013
Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions
CE Forristal, KL Wright, NA Hanley, ROC Oreffo, FD Houghton
Reproduction (Cambridge, England) 139 (1), 85, 2010
Nanotopographical control of stem cell differentiation
LE McNamara, RJ McMurray, MJP Biggs, F Kantawong, ROC Oreffo, ...
Journal of tissue engineering 1 (1), 120623, 2010
Association between the abnormal expression of matrix‐degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions
HI Roach, N Yamada, KSC Cheung, S Tilley, NMP Clarke, ROC Oreffo, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2005
Osteoprogenitor response to semi-ordered and random nanotopographies
MJ Dalby, D McCloy, M Robertson, H Agheli, D Sutherland, S Affrossman, ...
Biomaterials 27 (15), 2980-2987, 2006
Activation of the bone-derived latent TGF beta complex by isolated osteoclasts
ROC Oreffo, GR Mundy, SM Seyedin, LF Bonewald
Biochemical and biophysical research communications 158 (3), 817-823, 1989
Human osteoprogenitor growth and differentiation on synthetic biodegradable structures after surface modification
XB Yang, HI Roach, NMP Clarke, SM Howdle, R Quirk, KM Shakesheff, ...
Bone 29 (6), 523-531, 2001
Osteoprogenitor response to defined topographies with nanoscale depths
MJ Dalby, D McCloy, M Robertson, CDW Wilkinson, ROC Oreffo
Biomaterials 27 (8), 1306-1315, 2006
Clay: new opportunities for tissue regeneration and biomaterial design
JI Dawson, ROC Oreffo
Advanced Materials 25 (30), 4069-4086, 2013
The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells
MJP Biggs, RG Richards, N Gadegaard, CDW Wilkinson, ROC Oreffo, ...
Biomaterials 30 (28), 5094-5103, 2009
Mesenchymal stem cells: lineage, plasticity, and skeletal therapeutic potential
ROC Oreffo, C Cooper, C Mason, M Clements
Stem cell reviews 1, 169-178, 2005
Fabrication of pillar-like titania nanostructures on titanium and their interactions with human skeletal stem cells
T Sjöström, MJ Dalby, A Hart, R Tare, ROC Oreffo, B Su
Acta biomaterialia 5 (5), 1433-1441, 2009
The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation
JM Kanczler, PJ Ginty, L White, NMP Clarke, SM Howdle, KM Shakesheff, ...
Biomaterials 31 (6), 1242-1250, 2010
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