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Cris Lapthorn
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Ion mobility spectrometry‐mass spectrometry (IMS‐MS) of small molecules: Separating and assigning structures to ions
C Lapthorn, F Pullen, BZ Chowdhry
Mass Spectrometry Reviews 32 (1), 43-71, 2012
4342012
Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense
SA Moschos, M Frick, B Taylor, P Turnpenny, H Graves, KG Spink, ...
Molecular Therapy 19 (12), 2163-2168, 2011
1062011
Combining density functional theory (DFT) and collision cross-section (CCS) calculations to analyze the gas-phase behaviour of small molecules and their protonation site isomers
J Boschmans, S Jacobs, JP Williams, M Palmer, K Richardson, K Giles, ...
Analyst 141 (13), 4044-4054, 2016
1032016
Click-enabled heterotrifunctional template for sequential bioconjugations.
DM Beal, VE Albrow, G Burslem, L Hitchen, C Fernandes, C Lapthorn, ...
Org. Biomol. Chem., 548-554, 2011
752011
Can ion mobility mass spectrometry and density functional theory help elucidate protonation sites in 'small' molecules?
C Lapthorn, TJ Dines, BZ Chowdhry, GL Perkins, FS Pullen
Rapid Communications in Mass Spectrometry 27 (21), 2399-2410, 2013
672013
How useful is molecular modelling in combination with ion mobility mass spectrometry for ‘small molecule’ion mobility collision cross-sections?
C Lapthorn, FS Pullen, BZ Chowdhry, P Wright, GL Perkins, Y Heredia
Analyst 140 (20), 6814-6823, 2015
662015
Deep Sequencing Insights in Therapeutic shRNA Processing and siRNA Target Cleavage Precision
H Denise, SA Moschos, B Sidders, F Burden, H Perkins, N Carter, ...
Mol Ther Nucleic Acids 3 (e145), 2014
252014
" Soft" or" hard" ionisation? Investigation of metastable gas temperature effect on direct analysis in real-time analysis of Voriconazole.
C Lapthorn, F Pullen
European journal of mass spectrometry (Chichester, England) 15 (5), 587-593, 2009
152009
Current status and future prospects for ion-mobility mass spectrometry in the biopharmaceutical industry
K Skeene, K Khatri, Z Soloviev, C Lapthorn
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1869 (12), 140697, 2021
122021
Investigation into Small Molecule Isomeric Glucuronide Metabolite Differentiation Using In Silico and Experimental Collision Cross-Section Values
JRFB Connolly, J Munoz-Muriedas, C Lapthorn, D Higton, JPC Vissers, ...
Journal of the American Society for Mass Spectrometry 32 (8), 1976-1986, 2021
122021
The application of new approaches to the analysis of deposits from the Jet Fuel Thermal Oxidation Tester (JFTOT)
J Barker, J Reid, SA Smith, C Snape, D Scurr, G Langley, K Patel, ...
SAE International Journal of Fuels and Lubricants 10 (3), 741-755, 2017
122017
High performance liquid chromatography coupled to electrospray ionisation mass spectrometry method for the detection of salivary human neutrophil alpha defensins HNP1, HNP2 …
N Ashrafi, C Lapthorn, FS Pullen, F Naclerio, BV Nielsen
Analytical Methods 9 (46), 6482-6490, 2017
42017
The 38th BMSS Annual Meeting, Royal Northern College of Music Manchester: 5th to 7th September 2017
P Wright, H Britt, C Lapthorn, C Whitmore
European Journal of Mass Spectrometry 24 (2), 243-247, 2018
2018
Evaluation of human salivary alpha-defensins by LC-ESI-MS
N Ashrafi, C Lapthorn, F Naclerio, F Pullen, B Nielsen, Y Fu, J Miller, ...
PROTEIN SCIENCE 24, 302-303, 2015
2015
Validation of a LC-MS method for the detection of human salivary alpha-defensins
N Ashrafi, C Lapthorn, B Nielsen, F Naclerio, F Pullen, P Wright
PROTEIN SCIENCE 24, 303-304, 2015
2015
Correlation between potential human neutrophil antimicrobial peptides (HNP 1-3) and stress hormones in human saliva
N Ashrafi, F Pullen, B Nielse, C Lapthorn, F Naclario
PROTEIN SCIENCE 24, 305-305, 2015
2015
The effect of charge location in ion mobility mass spectrometry for small molecule analytes
C Lapthorn, F Pullen, B Chowdhry, G Perkins, T Dines, M McCullagh
2014
BACKGROUND: WHAT ROLE DO DEFENSINS HAVE IN INNATE IMMUNITY?
N Ashrafi, F Naclerio, J Miller, M Seijo, C Watkinson, L Fu, J Smith, ...
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