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Jacinth Naidoo
Jacinth Naidoo
Verified email at utsouthwestern.edu
Title
Cited by
Cited by
Year
Discovery of a proneurogenic, neuroprotective chemical
AA Pieper, S Xie, E Capota, SJ Estill, J Zhong, JM Long, GL Becker, ...
Cell 142 (1), 39-51, 2010
4292010
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
TH Scheuermann, Q Li, HW Ma, J Key, L Zhang, R Chen, JA Garcia, ...
Nature chemical biology 9 (4), 271-276, 2013
3162013
Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration
Y Zhang, A Desai, SY Yang, KB Bae, MI Antczak, SP Fink, S Tiwari, ...
Science 348 (6240), aaa2340, 2015
2872015
P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage
G Wang, T Han, D Nijhawan, P Theodoropoulos, J Naidoo, S Yadavalli, ...
Cell 158 (6), 1324-1334, 2014
2592014
Development of proneurogenic, neuroprotective small molecules
KS MacMillan, J Naidoo, J Liang, L Melito, NS Williams, L Morlock, ...
Journal of the American Chemical Society 133 (5), 1428-1437, 2011
2112011
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis
R Tesla, HP Wolf, P Xu, J Drawbridge, SJ Estill, P Huntington, ...
Proceedings of the National Academy of Sciences 109 (42), 17016-17021, 2012
1782012
The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis
AK Walker, PD Rivera, Q Wang, JC Chuang, S Tran, ...
Molecular psychiatry 20 (4), 500-508, 2015
1712015
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease
H De Jesús-Cortés, P Xu, J Drawbridge, SJ Estill, P Huntington, S Tran, ...
Proceedings of the National Academy of Sciences 109 (42), 17010-17015, 2012
1712012
Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor
JL Rogers, L Bayeh, TH Scheuermann, J Longgood, J Key, J Naidoo, ...
Journal of medicinal chemistry 56 (4), 1739-1747, 2013
1412013
Metabolomics of tomato xylem sap during bacterial wilt reveals Ralstonia solanacearum produces abundant putrescine, a metabolite that accelerates wilt disease
TM Lowe‐Power, CG Hendrich, E von Roepenack‐Lahaye, B Li, D Wu, ...
Environmental microbiology 20 (4), 1330-1349, 2018
1292018
P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury
TC Yin, JK Britt, H De Jesús-Cortés, Y Lu, RM Genova, MZ Khan, ...
Cell reports 8 (6), 1731-1740, 2014
1252014
Small-molecule activation of the TRAIL receptor DR5 in human cancer cells
G Wang, X Wang, H Yu, S Wei, N Williams, DL Holmes, R Halfmann, ...
Nature chemical biology 9 (2), 84-89, 2013
1172013
Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury
MO Blaya, HM Bramlett, J Naidoo, AA Pieper, WD Dietrich
Journal of neurotrauma 31 (5), 476-486, 2014
1032014
Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243
LM Dutca, SF Stasheff, A Hedberg-Buenz, DS Rudd, N Batra, FR Blodi, ...
Investigative ophthalmology & visual science 55 (12), 8330-8341, 2014
932014
Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses
P Luthra, J Naidoo, CA Pietzsch, S De, S Khadka, M Anantpadma, ...
Antiviral research 158, 288-302, 2018
852018
Discovery of a Neuroprotective Chemical, (S)-N-(3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(−)-P7C3-S243], with Improved …
J Naidoo, H De Jesus-Cortes, P Huntington, S Estill, LK Morlock, ...
Journal of medicinal chemistry 57 (9), 3746-3754, 2014
762014
Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease
D Jesús-Cortés, AD Miller, JK Britt, AJ DeMarco, E Stuebing, J Naidoo, ...
NPJ Parkinson's disease 1 (1), 1-6, 2015
522015
Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury
SWP Kemp, M Szynkaruk, KN Stanoulis, MD Wood, EH Liu, MP Willand, ...
Neuroscience 284, 202-216, 2015
502015
Spermidine promotes Bacillus subtilis biofilm formation by activating expression of the matrix regulator slrR
L Hobley, B Li, JL Wood, SH Kim, J Naidoo, AS Ferreira, M Khomutov, ...
Journal of Biological Chemistry 292 (29), 12041-12053, 2017
492017
A kinetic study of the reaction of atomic oxygen with SO2
J Naidoo, A Goumri, P Marshall
Proceedings of the Combustion Institute 30 (1), 1219-1225, 2005
442005
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