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Thomas Brabletz
Thomas Brabletz
Verified email at fau.de
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Year
A reciprocal repression between ZEB1 and members of the miR‐200 family promotes EMT and invasion in cancer cells
U Burk, J Schubert, U Wellner, O Schmalhofer, E Vincan, S Spaderna, ...
EMBO reports 9 (6), 582-589, 2008
20252008
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
U Wellner, J Schubert, UC Burk, O Schmalhofer, F Zhu, A Sonntag, ...
Nature cell biology 11 (12), 1487-1495, 2009
19202009
EMT in cancer
T Brabletz, R Kalluri, MA Nieto, RA Weinberg
Nature Reviews Cancer 18 (2), 128-134, 2018
17782018
Migrating cancer stem cells—an integrated concept of malignant tumour progression
T Brabletz, A Jung, S Spaderna, F Hlubek, T Kirchner
Nature Reviews Cancer 5 (9), 744-749, 2005
17142005
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
T Brabletz, A Jung, S Reu, M Porzner, F Hlubek, LA Kunz-Schughart, ...
Proceedings of the National Academy of Sciences 98 (18), 10356-10361, 2001
13942001
Guidelines and definitions for research on epithelial–mesenchymal transition
J Yang, P Antin, G Berx, C Blanpain, T Brabletz, M Bronner, K Campbell, ...
Nature reviews Molecular cell biology 21 (6), 341-352, 2020
13642020
Oncogenic roles of EMT-inducing transcription factors
A Puisieux, T Brabletz, J Caramel
Nature cell biology 16 (6), 488-494, 2014
10622014
Wnt/β-catenin signaling in cancer stemness and malignant behavior
R Fodde, T Brabletz
Current opinion in cell biology 19 (2), 150-158, 2007
9932007
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
O Schmalhofer, S Brabletz, T Brabletz
Cancer and Metastasis Reviews 28, 151-166, 2009
9462009
β-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
T Brabletz, A Jung, S Dag, F Hlubek, T Kirchner
The American journal of pathology 155 (4), 1033-1038, 1999
8931999
The ZEB/miR‐200 feedback loop—a motor of cellular plasticity in development and cancer?
S Brabletz, T Brabletz
EMBO reports 11 (9), 670-677, 2010
8892010
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
AM Krebs, J Mitschke, M Lasierra Losada, O Schmalhofer, M Boerries, ...
Nature cell biology 19 (5), 518-529, 2017
8782017
The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
K Aigner, B Dampier, L Descovich, M Mikula, A Sultan, M Schreiber, ...
Oncogene 26 (49), 6979-6988, 2007
7482007
Wnt signalling induces maturation of Paneth cells in intestinal crypts
JH van Es, P Jay, A Gregorieff, ME van Gijn, S Jonkheer, P Hatzis, ...
Nature cell biology 7 (4), 381-386, 2005
7362005
Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and β-catenin
T Brabletz, F Hlubek, S Spaderna, O Schmalhofer, E Hiendlmeyer, A Jung, ...
Cells tissues organs 179 (1-2), 56-65, 2005
6952005
To differentiate or not—routes towards metastasis
T Brabletz
Nature Reviews Cancer 12 (6), 425-436, 2012
6862012
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
S Spaderna, O Schmalhofer, M Wahlbuhl, A Dimmler, K Bauer, A Sultan, ...
Cancer research 68 (2), 537-544, 2008
6672008
A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer
S Spaderna, O Schmalhofer, F Hlubek, G Berx, A Eger, S Merkel, A Jung, ...
Gastroenterology 131 (3), 830-840, 2006
5602006
EMT and MET in metastasis: where are the cancer stem cells?
T Brabletz
Cancer cell 22 (6), 699-701, 2012
4932012
L1, a novel target of β-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers
N Gavert, M Conacci-Sorrell, D Gast, A Schneider, P Altevogt, T Brabletz, ...
The Journal of cell biology 168 (4), 633-642, 2005
4682005
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