Frank Westermann

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Benedikt BrorsDivision of Applied Bioinformatics, German Cancer Research Center DKFZ HeidelbergVerified email at dkfz.de
Jo Vandesompeleprofessor in functional cancer genomics and applied bioinformaticsVerified email at ugent.be
Javed KhanDeputy Branch Chief Genetics Branch, Senior Investigator, Center for Cancer Research, NCI, NIHVerified email at mail.nih.gov
Katleen De Preterfull research professor, Ghent UniversityVerified email at ugent.be
Pieter Mestdaghpostdoctoral fellow, Ghent UniversityVerified email at ugent.be
Axel BennerDKFZ HeidelbergVerified email at dkfz-heidelberg.de
Stefan M. PfisterProfessor of Pediatrics, Hopp-Children´s Cancer Center Heidelberg (KiTZ)Verified email at kitz-heidelberg.de
Roland EilsProfessor for Digital Health, Charité-Universitätsmedizin Berlin and Berlin Institute of HealthVerified email at charite.de
Sven BilkeIllumina Inc.Verified email at illumina.com
Marcel KoolPI, Hopp Children's Cancer Center Heidelberg & Princess Maxima Center Pediatric Oncology UtrechtVerified email at dkfz.de
Annette Kopp-SchneiderHead, Division of Biostatistics, German Cancer Research Center (DKFZ), HeidelbergVerified email at dkfz.de
D CatchpooleHead, Tumour Bank, The Children's Hospital at WestmeadVerified email at health.nsw.gov.au
Markus RingnérScience for Life Laboratory and Lund UniversityVerified email at scilifelab.se
Carsten PetersonProfessor, Computational Biology, Theoretical Physics, Lund UniversityVerified email at thep.lu.se
Lao H SaalAssociate Professor, Lund UniversityVerified email at med.lu.se
Thomas HielscherDKFZ, German Cancer Research Center, Division of BiostatisticsVerified email at dkfz.de
Melinda HalaszAssistant Professor, UCD School of MedicineVerified email at ucd.ie
Li MaProfessor, The University of Texas MD Anderson Cancer CenterVerified email at mdanderson.org
Robert A. WeinbergMITVerified email at wi.mit.edu
Sven LindnerUniversity Hospital EssenVerified email at ruhr-uni-bochum.de

Frank Westermann

Associate Professor of Tumor Biology and Personalized Medicine

Verified email at dkfz.de - Homepage

Childhood Cancer Neuroendocrine Development Oncogenes Epigenetics Personalized Oncology


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Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks J Khan, JS Wei, M Ringner, LH Saal, M Ladanyi, F Westermann, ... Nature medicine 7 (6), 673-679, 2001	3455	2001
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis L Ma, J Young, H Prabhala, E Pan, P Mestdagh, D Muth, ... Nature cell biology 12 (3), 247-256, 2010	1570	2010
A novel and universal method for microRNA RT-qPCR data normalization P Mestdagh, P Van Vlierberghe, A De Weer, D Muth, F Westermann, ... Genome biology 10 (6), 1-10, 2009	1115	2009
The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018	1046	2018
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models Nature biotechnology 28 (8), 827-838, 2010	804	2010
Telomerase activation by genomic rearrangements in high-risk neuroblastoma M Peifer, F Hertwig, F Roels, D Dreidax, M Gartlgruber, R Menon, ... Nature 526 (7575), 700-704, 2015	530	2015
Histone deacetylase 8 in neuroblastoma tumorigenesis I Oehme, HE Deubzer, D Wegener, D Pickert, JP Linke, B Hero, ... Clinical Cancer Research 15 (1), 91-99, 2009	425	2009
Neuroblastoma: biology and molecular and chromosomal pathology M Schwab, F Westermann, B Hero, F Berthold The lancet oncology 4 (8), 472-480, 2003	394	2003
Mutational dynamics between primary and relapse neuroblastomas A Schramm, J Köster, Y Assenov, K Althoff, M Peifer, E Mahlow, ... Nature genetics 47 (8), 872-877, 2015	345	2015
Customized oligonucleotide microarray gene expression–based classification of neuroblastoma patients outperforms current clinical risk stratification A Oberthuer, F Berthold, P Warnat, B Hero, Y Kahlert, R Spitz, K Ernestus, ... Journal of clinical oncology 24 (31), 5070-5078, 2006	307	2006
Next-generation personalised medicine for high-risk paediatric cancer patients–The INFORM pilot study BC Worst, CM van Tilburg, GP Balasubramanian, P Fiesel, R Witt, ... European journal of cancer 65, 91-101, 2016	276	2016
Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas F Westermann, D Muth, A Benner, T Bauer, KO Henrich, A Oberthuer, ... Genome biology 9 (10), 1-14, 2008	259	2008
Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia P Nürnberg, H Thiele, D Chandler, W Höhne, ML Cunningham, H Ritter, ... Nature genetics 28 (1), 37-41, 2001	255	2001
Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma JS Wei, BT Greer, F Westermann, SM Steinberg, CG Son, QR Chen, ... Cancer research 64 (19), 6883-6891, 2004	251	2004
Genetic parameters of neuroblastomas F Westermann, M Schwab Cancer letters 184 (2), 127-147, 2002	231	2002
A mechanistic classification of clinical phenotypes in neuroblastoma S Ackermann, M Cartolano, B Hero, A Welte, Y Kahlert, A Roderwieser, ... Science 362 (6419), 1165-1170, 2018	220	2018
Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma H Kocak, S Ackermann, B Hero, Y Kahlert, A Oberthuer, D Juraeva, ... Cell death & disease 4 (4), e586-e586, 2013	203	2013
FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma M Remke, T Hielscher, A Korshunov, PA Northcott, S Bender, M Kool, ... J Clin Oncol 29 (29), 3852-3861, 2011	181	2011
Targeting MYCN-driven transcription by BET-bromodomain inhibition A Henssen, K Althoff, A Odersky, A Beckers, R Koche, F Speleman, ... Clinical Cancer Research 22 (10), 2470-2481, 2016	165	2016
MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival EA Afanasyeva, P Mestdagh, C Kumps, J Vandesompele, V Ehemann, ... Cell Death & Differentiation 18 (6), 974-984, 2011	160	2011

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