Biodegradable ionic liquids Part II. Effect of the anion and toxicology MT Garcia, N Gathergood, PJ Scammells Green Chemistry 7 (1), 9-14, 2005 | 732 | 2005 |
Biodegradable ionic liquids: Part I. Concept, preliminary targets and evaluation N Gathergood, MT Garcia, PJ Scammells Green Chemistry 6 (3), 166-175, 2004 | 644 | 2004 |
Biodegradable ionic liquids Part III. The first readily biodegradable ionic liquids N Gathergood, PJ Scammells, MT Garcia Green Chemistry 8 (2), 156-160, 2006 | 405 | 2006 |
Ionic liquids: the neglected issues PJ Scammells, JL Scott, RD Singer Australian Journal of Chemistry 58 (3), 155-169, 2005 | 371 | 2005 |
The role of kinetic context in apparent biased agonism at GPCRs C Klein Herenbrink, DA Sykes, P Donthamsetti, M Canals, T Coudrat, ... Nature communications 7 (1), 10842, 2016 | 347 | 2016 |
Structure of the adenosine A1 receptor reveals the basis for subtype selectivity A Glukhova, DM Thal, AT Nguyen, EA Vecchio, M Jörg, PJ Scammells, ... Cell 168 (5), 867-877. e13, 2017 | 296 | 2017 |
A Novel Mechanism of G Protein-coupled Receptor Functional Selectivity: MUSCARINIC PARTIAL AGONIST McN-A-343 AS A BITOPIC ORTHOSTERIC/ALLOSTERIC LIGAND∗ C Valant, KJ Gregory, NE Hall, PJ Scammells, MJ Lew, PM Sexton, ... Journal of Biological Chemistry 283 (43), 29312-29321, 2008 | 201 | 2008 |
Biodegradable pyridinium ionic liquids: design, synthesis and evaluation JR Harjani, RD Singer, MT Garcia, PJ Scammells Green Chemistry 11 (1), 83-90, 2009 | 198 | 2009 |
Design and preparation of room-temperature ionic liquids containing biodegradable side chains N Gathergood, PJ Scammells Australian Journal of Chemistry 55 (9), 557-560, 2002 | 192 | 2002 |
Phosphonium ionic liquids: design, synthesis and evaluation of biodegradability F Atefi, MT Garcia, RD Singer, PJ Scammells Green Chemistry 11 (10), 1595-1604, 2009 | 166 | 2009 |
Ionic liquids provide unique opportunities for oral drug delivery: structure optimization and in vivo evidence of utility HD Williams, Y Sahbaz, L Ford, TH Nguyen, PJ Scammells, CJH Porter Chemical Communications 50 (14), 1688-1690, 2014 | 156 | 2014 |
2-Amino-3-benzoylthiophene allosteric enhancers of A1 adenosine agonist binding: new 3, 4-, and 5-modifications H Lütjens, A Zickgraf, H Figler, J Linden, RA Olsson, PJ Scammells Journal of medicinal chemistry 46 (10), 1870-1877, 2003 | 152 | 2003 |
Transformation of poorly water-soluble drugs into lipophilic ionic liquids enhances oral drug exposure from lipid based formulations Y Sahbaz, HD Williams, TH Nguyen, J Saunders, L Ford, SA Charman, ... Molecular pharmaceutics 12 (6), 1980-1991, 2015 | 148 | 2015 |
Further investigation of the biodegradability of imidazolium ionic liquids JR Harjani, J Farrell, MT Garcia, RD Singer, PJ Scammells Green Chemistry 11 (6), 821-829, 2009 | 140 | 2009 |
Allosteric Modulators of the Adenosine A1 Receptor: Synthesis and Pharmacological Evaluation of 4-Substituted 2-Amino-3-benzoylthiophenes L Aurelio, C Valant, BL Flynn, PM Sexton, A Christopoulos, PJ Scammells Journal of medicinal chemistry 52 (14), 4543-4547, 2009 | 134 | 2009 |
A Monod-Wyman-Changeux mechanism can explain G protein-coupled receptor (GPCR) allosteric modulation M Canals, JR Lane, A Wen, PJ Scammells, PM Sexton, A Christopoulos Journal of Biological Chemistry 287 (1), 650-659, 2012 | 132 | 2012 |
A new mechanism of allostery in a G protein–coupled receptor dimer JR Lane, P Donthamsetti, J Shonberg, CJ Draper-Joyce, S Dentry, ... Nature chemical biology 10 (9), 745-752, 2014 | 127 | 2014 |
2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers G Nikolakopoulos, H Figler, J Linden, PJ Scammells Bioorganic & medicinal chemistry 14 (7), 2358-2365, 2006 | 126 | 2006 |
Biased agonism at G protein‐coupled receptors: the promise and the challenges—a medicinal chemistry perspective J Shonberg, L Lopez, PJ Scammells, A Christopoulos, B Capuano, ... Medicinal research reviews 34 (6), 1286-1330, 2014 | 125 | 2014 |
Design strategies for bivalent ligands targeting GPCRs J Shonberg, PJ Scammells, B Capuano ChemMedChem 6 (6), 963-974, 2011 | 121 | 2011 |